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Found 68 with Last Name = 'giovani' and Initial = 's'
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50045200(CHEMBL3310712)
Affinity DataIC50:  600nMAssay Description:Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50045201(CHEMBL3310822)
Affinity DataIC50:  600nMAssay Description:Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494389(CHEMBL3086246)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494390(CHEMBL3086251)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50045202(CHEMBL3310709)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494395(CHEMBL3086247)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494398(CHEMBL3086249)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494390(CHEMBL3086251)
Affinity DataIC50: >7.00E+3nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP NFEV and APP K612V mutant assessed as generation of EV40/EV42 by electrochemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494391(CHEMBL3086250)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494396(CHEMBL3086248)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494389(CHEMBL3086246)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1 in HEK293 cells expressing APP NFEV and APP K612V mutant assessed as generation of EV40/EV42 by electrochemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494390(CHEMBL3086251)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells expressing APP NFEV and wild-type alpha cleavage site assessed as generation of EV40/EV42 by electrochemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494394(CHEMBL3086238)
Affinity DataIC50:  1.28E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494397(CHEMBL3086243)
Affinity DataIC50:  1.43E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494393(CHEMBL3086242)
Affinity DataIC50:  1.48E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494392(CHEMBL3086244)
Affinity DataIC50:  1.49E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494399(CHEMBL3086245)
Affinity DataIC50:  1.81E+4nMAssay Description:Inhibition of human recombinant BACE1 using [acetyl-C(W8044Eu)-EVNLDAEFK-QSY7] as substrate by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388064(CHEMBL1237284 | TCMDC-123970)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388063(CHEMBL2059468)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50045203(CHEMBL3310710)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388062(CHEMBL2059472)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388061(CHEMBL2057540)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388067(CHEMBL2059462)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388066(CHEMBL2059464)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50388065(CHEMBL1237282 | TCMDC-142139)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum SUB1 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSubtilisin-like protease 1(Plasmodium falciparum)
University Of Siena

Curated by ChEMBL
LigandPNGBDBM50045204(CHEMBL3310824)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of Plasmodium falciparum serine protease subtilisin-like protease 1by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University of Siena

Curated by ChEMBL
LigandPNGBDBM50494389(CHEMBL3086246)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of BACE1 in human SH-SY5Y cells expressing APP NFEV and wild-type alpha cleavage site assessed as generation of EV40/EV42 by electrochemil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561322(CHEMBL4741626)
Affinity DataEC50:  120nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561323(CHEMBL4761482)
Affinity DataEC50:  4.10E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561324(CHEMBL4744909)
Affinity DataEC50:  350nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561325(CHEMBL4783477)
Affinity DataEC50:  1.06E+4nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561326(CHEMBL4745080)
Affinity DataEC50:  6.00E+4nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561327(CHEMBL4750913)
Affinity DataEC50:  5.70E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561328(CHEMBL4796643)
Affinity DataEC50:  820nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561329(CHEMBL4740049)
Affinity DataEC50:  2.80E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561330(CHEMBL4787986)
Affinity DataEC50:  3.70E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561331(CHEMBL4799939)
Affinity DataEC50:  150nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561332(CHEMBL4747252)
Affinity DataEC50:  7.10E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561333(CHEMBL4791435)
Affinity DataEC50:  2.10E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561334(CHEMBL4755366)
Affinity DataEC50:  230nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561335(CHEMBL4757589)
Affinity DataEC50:  270nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561336(CHEMBL4741540)
Affinity DataEC50:  480nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561337(CHEMBL4759920)
Affinity DataEC50:  200nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561338(CHEMBL4762219)
Affinity DataEC50:  1.14E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561339(CHEMBL4780866)
Affinity DataEC50:  1.40E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561340(CHEMBL4780584)
Affinity DataEC50:  480nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561341(CHEMBL4745672)
Affinity DataEC50:  96nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561342(CHEMBL4795877)
Affinity DataEC50:  440nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561343(CHEMBL4796353)
Affinity DataEC50:  160nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
D3-Pharmachemistry

Curated by ChEMBL
LigandPNGBDBM50561344(CHEMBL4776837)
Affinity DataEC50:  1.90E+3nMAssay Description:Potentiation of human CFTR F508 deletion mutant expressed in rat FRT cells coexpressing HS-YFP assessed as increase in iodide influx pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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