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Found 114 with Last Name = 'morimoto' and Initial = 't'
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304410(CHEMBL594108 | cis-2-[(E)-4-(1H-Imidazol-1-yl)but-...)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304411(CHEMBL594109 | cis-2-{4-[(1H-Imidazol-1-yl)methyl]...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304417(CHEMBL593656 | CHEMBL593877 | cis-(+/-)-4-(3,4-Dim...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304412(CHEMBL595064 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304423(CHEMBL595272 | cis-4-(3,4-Dimethoxyphenyl)-2-[4-(m...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304413(CHEMBL596447 | cis-2-[4-(1,4-Dioxa-8-azaspiro[4.5]...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304419(CHEMBL592931 | cis-4-(3,4-Dimethoxyphenyl)-2-[2-(m...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304418(CHEMBL596394 | cis-4-(3,4-Dimethoxyphenyl)-2-[3-(m...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304415(CHEMBL595038 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232961(US9353113, 10(5))
Affinity DataIC50:  3.80nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM364551(US9862721, 10(5))
Affinity DataIC50:  3.80nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304422(CHEMBL605096 | cis-5-(3,4-Dimethoxyphenyl)-3-[4-(m...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232952(US9353113, 3(50) | US9862721, 3(50))
Affinity DataIC50:  4.5nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232952(US9353113, 3(50) | US9862721, 3(50))
Affinity DataIC50:  4.5nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232957(US9353113, 7(41) | US9862721, 7(41))
Affinity DataIC50:  4.90nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232957(US9353113, 7(41) | US9862721, 7(41))
Affinity DataIC50:  4.90nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155300(US9006246, 31(24) | US9636330, 31(24))
Affinity DataIC50:  5nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155300(US9006246, 31(24) | US9636330, 31(24))
Affinity DataIC50:  5nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232955(US9353113, 6(65) | US9862721, 6(65))
Affinity DataIC50:  5.10nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232955(US9353113, 6(65) | US9862721, 6(65))
Affinity DataIC50:  5.10nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304409(CHEMBL595959 | cis-2-{2-[2-(1H-Imidazol-1-yl)ethox...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232962(US9353113, 11(12) | US9862721, 11(12))
Affinity DataIC50:  5.40nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232962(US9353113, 11(12) | US9862721, 11(12))
Affinity DataIC50:  5.40nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155280(US9006246, 12(97) | US9636330, 12(97))
Affinity DataIC50:  6.70nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155280(US9006246, 12(97) | US9636330, 12(97))
Affinity DataIC50:  6.70nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155341(US9006246, 51(48) | US9636330, 51(48))
Affinity DataIC50:  7.80nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155341(US9006246, 51(48) | US9636330, 51(48))
Affinity DataIC50:  7.80nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232954(US9353113, 6(63) | US9862721, 6(63))
Affinity DataIC50:  8nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232954(US9353113, 6(63) | US9862721, 6(63))
Affinity DataIC50:  8nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304414(CHEMBL603626 | cis-4-(3,4-Dimethoxyphenyl)-2-[4-(p...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232963(US9353113, 11(24) | US9862721, 11(24))
Affinity DataIC50:  8.40nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232963(US9353113, 11(24) | US9862721, 11(24))
Affinity DataIC50:  8.40nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155279(US9006246, 12(42) | US9636330, 12(42))
Affinity DataIC50:  9.60nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155279(US9006246, 12(42) | US9636330, 12(42))
Affinity DataIC50:  9.60nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304416(CHEMBL595039 | cis-4-(3,4-Dimethoxyphenyl)-2-{4-[(...)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232953(US9353113, 6(53) | US9862721, 6(53))
Affinity DataIC50:  10nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232953(US9353113, 6(53) | US9862721, 6(53))
Affinity DataIC50:  10nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155303(US9006246, 31(127) | US9636330, 31(127))
Affinity DataIC50:  11nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155306(US9006246, 31(140) | US9636330, 31(140))
Affinity DataIC50:  11nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155306(US9006246, 31(140) | US9636330, 31(140))
Affinity DataIC50:  11nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155303(US9006246, 31(127) | US9636330, 31(127))
Affinity DataIC50:  11nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232959(US9353113, 9(1) | US9862721, 9(1))
Affinity DataIC50:  12nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232959(US9353113, 9(1) | US9862721, 9(1))
Affinity DataIC50:  12nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155310(US9006246, 31(169) | US9636330, 31(169))
Affinity DataIC50:  13nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM155310(US9006246, 31(169) | US9636330, 31(169))
Affinity DataIC50:  13nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM232964(US9353113, Ref. Ex. 2)
Affinity DataIC50:  14nMpH: 9.0Assay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM364554(US9862721, Ref. Ex. 2)
Affinity DataIC50:  14nMAssay Description:10 μL of a test compound solution (10% dimethyl sulfoxide) at each concentration and 40 μL of a 5 μg/mL human ENPP2 solution (buffer A...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Kyoto 601-8550

Curated by ChEMBL
LigandPNGBDBM50304408(CHEMBL605935 | N-[3-(1H-Imidazol-1-yl)propyl]-2-[c...)
Affinity DataIC50:  14.3nMAssay Description:Inhibition of human recombinant PDE4D catalytic domain cloned from human HL60 cells assessed as inhibition of cAMP hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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