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Found 112 with Last Name = 'szeto' and Initial = 't'
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM429328(ALP-POS-c59291d4-6 | CVD-0006355 | jm5b01461, Comp...)
Affinity DataKi:  70nMAssay Description:Non-covalent inhibition to SARS-CoV-2 -Mpro assessed as inhibition constant by native mass spectrometric analysisMore data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602444(CHEMBL5206501)
Affinity DataKi:  2.29E+3nMAssay Description:Non-covalent inhibition to SARS-CoV-2 -Mpro assessed as inhibition constant by native mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCathepsin K(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  0.260nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  4.40nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  6.5nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  12nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  28nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  28nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  42nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  43nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  44nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  44nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  51nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  51nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  54nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  54nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  69nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCalpain-1 catalytic subunit(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  74nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  99nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  100nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  100nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOrf1a protein(MERS-CoV)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-OC43)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  110nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-HKU1)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  120nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-NL63)
The University of Arizona

LigandPNGBDBM448319(GC-376 | GC376)
Affinity DataIC50:  120nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  130nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602444(CHEMBL5206501)
Affinity DataIC50:  200nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602445(CHEMBL5207542)
Affinity DataIC50:  280nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-NL63)
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  360nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(HCoV-NL63)
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  450nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602446(CHEMBL5178131)
Affinity DataIC50:  510nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602447(CHEMBL5169554)
Affinity DataIC50:  560nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602448(CHEMBL5186431)
Affinity DataIC50:  660nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602449(CHEMBL5201613)
Affinity DataIC50:  670nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602450(CHEMBL5172431)
Affinity DataIC50:  810nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602451(CHEMBL5189062)
Affinity DataIC50:  940nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602452(CHEMBL5208393)
Affinity DataIC50:  960nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602453(CHEMBL5179577)
Affinity DataIC50:  1.05E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM484194(UAWJ9-36-1)
Affinity DataIC50:  1.37E+3nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602454(CHEMBL5204664)
Affinity DataIC50:  1.48E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProcathepsin L(Homo sapiens (Human))
The University of Arizona

LigandPNGBDBM484195(UAWJ9-36-3)
Affinity DataIC50:  1.61E+3nMAssay Description:Enzymatic inhibition of GC-376, UAWJ9-36-1, and UAWJ9-36-3 against Mpro's from all seven human coronaviruses. Data fittings of the proteolytic progre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602455(CHEMBL5175491)
Affinity DataIC50:  1.81E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602456(CHEMBL5198265)
Affinity DataIC50:  1.97E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602457(CHEMBL5195867)
Affinity DataIC50:  2.14E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602458(CHEMBL5180821)
Affinity DataIC50:  2.39E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602459(CHEMBL5196047)
Affinity DataIC50:  2.47E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
The University Of Arizona

Curated by ChEMBL
LigandPNGBDBM50602460(CHEMBL5193830)
Affinity DataIC50:  2.51E+3nMAssay Description:Non-covalent inhibition of SARS-Cov-2 -Mpro incubated for 30 mins using FRET substrate measured for 1 hr by FRET-based enzymatic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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