Compile Data Set for Download or QSAR
maximum 50k data
Found 66 with Last Name = 'ali' and Initial = 'tfs'
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50152068(CHEMBL3781485)
Affinity DataIC50:  10nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50540056(CHEMBL4638983)
Affinity DataIC50:  28nMAssay Description:Inhibition of human SIRT2 expressed in Escherichia coli BL21 using acetyl-H3K9 by HPLC based assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM5446(CHEMBL553 | ERLOTINIB HYDROCHLORIDE | Erlotinib | ...)
Affinity DataIC50:  60nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50:  70nMAssay Description:Inhibition of human SIRT2 deacetylase activity using QPKKac as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610747(CHEMBL5274785)
Affinity DataIC50:  70nMAssay Description:Inhibition of human SIRT2 deacetylase activity using QPKKac as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610744(CHEMBL5267372)
Affinity DataIC50:  78nMAssay Description:Inhibition of human SIRT2 deacetylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610746(CHEMBL5286760)
Affinity DataIC50:  90nMAssay Description:Inhibition of human SIRT2 demyristoylation activity using ETDKac as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610745(CHEMBL5273182)
Affinity DataIC50:  93nMAssay Description:Inhibition of human SIRT2 deacetylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610745(CHEMBL5273182)
Affinity DataIC50:  110nMAssay Description:Inhibition of human SIRT2 defatty-acylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610744(CHEMBL5267372)
Affinity DataIC50:  170nMAssay Description:Inhibition of human SIRT2 defatty-acylase activity measured after preincubation by HPLC methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610742(CHEMBL5273854)
Affinity DataIC50:  180nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using (FAM)-labeled fluorescent peptide-RHKK(Ac)LM by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50148781(CHEMBL3770903)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610743(CHEMBL5272503)
Affinity DataIC50:  460nMAssay Description:Inhibition of human GST-fused SIRT2 expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517778(CHEMBL4447196)
Affinity DataIC50:  500nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517776(CHEMBL4449599)
Affinity DataIC50:  540nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517774(CHEMBL4462971)
Affinity DataIC50:  700nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610738(CHEMBL5282160)
Affinity DataIC50:  980nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50595087(CHEMBL5192844)
Affinity DataIC50:  1.17E+3nMAssay Description:Inhibition of human SIRT2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517771(CHEMBL4585048)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610748(CHEMBL5266407)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human SIRT2 using Ac-peptide as substrate assessed as fluorescence intensity by microplate readerMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523795(CHEMBL4551537)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517773(CHEMBL4588486)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610737(CHEMBL4444068)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517777(CHEMBL4464785)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523787(CHEMBL4464347)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using RHKK(Ac)-MCA as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523787(CHEMBL4464347)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase Chk2(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517776(CHEMBL4449599)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610750(CHEMBL5276776)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of human SIRT2 using Ac-Glu-Thr-Asp-Lys(Dec)-AMC as substrate by fluorogenic based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523797(CHEMBL4522115)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517770(CHEMBL4474429)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517775(CHEMBL4540070)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Al-Azhar University

Curated by ChEMBL
LigandPNGBDBM50517772(CHEMBL4568408)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of His6-tagged EGFR cytoplasmic domain (645 to 1186 residues) (unknown origin) expressed in baculovirus infected Sf9 insect cells after 10...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610747(CHEMBL5274785)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of human SIRT2 demyristoylation activity using ETDKac as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523789(CHEMBL4562248)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50241453(1,3,6,7-tetrahydroxy-2,8-bis(3-methylbut-2-enyl)-9...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human SIRT2 using sirtuin substrate incubated for 30 mins by enzymatic fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610749(CHEMBL5269160)
Affinity DataIC50:  3.81E+3nMAssay Description:Inhibition of human SIRT2 expressed in Escherichia coli BL21(DE3) using Ac-Arg-His-Lys-[Lys-(Ac)]-AMC substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523802(CHEMBL3604372)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using RHKK(Ac)-MCA as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523794(CHEMBL4563921)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523790(CHEMBL4456341)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523800(CHEMBL4527063)
Affinity DataIC50:  6.70E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610741(CHEMBL5289020)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using (FAM)-labeled fluorescent peptide-RHKK(Ac)LM by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523786(CHEMBL4449841)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50553465(CHEMBL4779549)
Affinity DataIC50:  7.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-labeled RHKK(Ac) LM peptide as substrate incubated for 60 mins by electrophoretic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50553470(CHEMBL4749343)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-labeled RHKK(Ac) LM peptide as substrate incubated for 60 mins by electrophoretic mobility...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523798(CHEMBL3604373)
Affinity DataIC50:  8.80E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using RHKK(Ac)-MCA as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of human SIRT2 using sirtuin substrate incubated for 30 mins by enzymatic fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610739(CHEMBL5277171)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using (FAM)-labeled fluorescent peptide-RHKK(Ac)LM by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610736(CHEMBL5273711)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50523791(CHEMBL4473932)
Affinity DataIC50:  1.02E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using FAM-RHKK(Ac)LM as substrate measured after 60 mins by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))TBA
LigandPNGBDBM50610740(CHEMBL5266797)
Affinity DataIC50:  1.08E+4nMAssay Description:Inhibition of recombinant SIRT2 (unknown origin) using (FAM)-labeled fluorescent peptide-RHKK(Ac)LM by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 66 total ) | Next | Last >>
Jump to: