TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 0.497nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 3.60nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of HIV1 integrase strand transfer activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 5.70nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 6.80nMAssay Description:Inhibition of vitronectin binding to human integrin alphaVbeta3 measured after 4 hrs by ELISAMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of HIV1 integrase 3'-end processing activity after 1 hr by densitometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Tokyo Medical And Dental University
Curated by ChEMBL
Tokyo Medical And Dental University
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of vitronectin binding to integrin alphaVbeta3 in HDF pretreated for 20 mins followed by vitronectin addition measured after 40 mins by cr...More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Competitive inhibition of TAMRAAc-TZ14011 binding to CXCR4 (unknown origin) expressed in CHO cells in presence of ZnCl2 by NanoBRET assay relative to...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Displacement of fluorescently-labeled-TZ14011 from CXCR4 in human Jurkat cells incubated for 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Tokyo Medical And Dental University (Tmdu)
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Displacement of fluorescently-labeled-TZ14011 from CXCR4 in human Jurkat cells incubated for 30 mins by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase 3'-processing activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of HIV1 integrase strand transfer activity expressed in Escherichia coli after 60 minsMore data for this Ligand-Target Pair