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TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM257207(US9493440, 51)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603022(CHEMBL5187271)
Affinity DataIC50:  1nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603035(CHEMBL5177346)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603031(CHEMBL5201248)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603036(CHEMBL5207998)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM257207(US9493440, 51)
Affinity DataIC50:  1nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603037(CHEMBL5194735)
Affinity DataIC50: <1nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603028(CHEMBL5182227)
Affinity DataIC50:  2nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603017(CHEMBL5206337)
Affinity DataIC50:  2nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603021(CHEMBL5170359)
Affinity DataIC50:  2nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603020(CHEMBL5196967)
Affinity DataIC50:  3nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603034(CHEMBL5169946)
Affinity DataIC50:  3nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603040(CHEMBL5208819)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603042(CHEMBL5179131)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603005(CHEMBL5176421)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50602999(CHEMBL5179734)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603032(CHEMBL5171585)
Affinity DataIC50:  4nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603043(CHEMBL5179942)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603022(CHEMBL5187271)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603018(CHEMBL5200822)
Affinity DataIC50:  5nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603013(CHEMBL5174552)
Affinity DataIC50:  6nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603004(CHEMBL5169393)
Affinity DataIC50:  6nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499493(CHEMBL3739648)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at P2X7R in human whole blood assessed as inhibition of LPS-induced IL-1beta production incubated for 30 mins followed by ATP add...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482847(CHEMBL1258135)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482849(CHEMBL1258364)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482847(CHEMBL1258135)
Affinity DataIC50:  6nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50602997(CHEMBL5182980)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482853(CHEMBL1258814)
Affinity DataIC50:  7nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603009(CHEMBL5184816)
Affinity DataIC50:  7nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603021(CHEMBL5170359)
Affinity DataIC50:  7nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603014(CHEMBL5209350)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603012(CHEMBL5169734)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603038(CHEMBL5198808)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482845(CHEMBL1257905)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482845(CHEMBL1257905)
Affinity DataIC50:  8nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603037(CHEMBL5194735)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603035(CHEMBL5177346)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603008(CHEMBL5182067)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499492(CHEMBL3740684)
Affinity DataIC50:  8nMAssay Description:Antagonist activity at human P2X7R expressed in BzATP-stimulated human 1321N1 cells incubated for 20 mins followed by BzATP stimulation measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499491(CHEMBL3741668)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human P2X7R expressed in BzATP-stimulated human 1321N1 cells incubated for 20 mins followed by BzATP stimulation measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499501(CHEMBL3741934)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human P2X7R expressed in BzATP-stimulated human 1321N1 cells incubated for 20 mins followed by BzATP stimulation measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499502(CHEMBL3740237)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human P2X7R expressed in BzATP-stimulated human 1321N1 cells incubated for 20 mins followed by BzATP stimulation measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50499504(CHEMBL3741412)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at human P2X7R expressed in BzATP-stimulated human 1321N1 cells incubated for 20 mins followed by BzATP stimulation measured ever...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482842(CHEMBL1257316)
Affinity DataIC50:  9nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603027(CHEMBL5201629)
Affinity DataIC50:  9nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603001(CHEMBL5186450)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length LRRK2 G2019S mutant (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603017(CHEMBL5206337)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482824(CHEMBL1258931)
Affinity DataIC50:  11nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50603036(CHEMBL5207998)
Affinity DataIC50:  11nMAssay Description:Inhibition of full length wild type LRRK2 (unknown origin) by LRRKtide Adapta assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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