Affinity DataIC50: 3.30nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant BACE1 by FRET assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.0830nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Mus musculus)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.420nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Mus musculus)
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Tokyo University of Pharmacy and Life Sciences
Curated by ChEMBL
Affinity DataEC50: 8.90nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by dibutyryl cyclic adenosine 3', 5...More data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.25nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as induction of Ca2+ flux after 18 hrs by Fluo-4 AM dye based FLIPR assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.20nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by Fluo-4-AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 6.40nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by Fluo-4-AM dye based calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 3.20nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.170nMAssay Description:Antisecretory activity evaluated by the inhibition of 14C -AP uptake in isolated rabbit parietal cells stimulated by exogenous histamineMore data for this Ligand-Target Pair