Found 56 with Last Name = 'antane' and Initial = 'm' 
Affinity DataIC50: 0.170nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 0.410nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Compound was evaluated for the in vitro inhibition of specific binding of [125I]-A II to Angiotensin II receptor, type 1 from rat adrenal membranes.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 285nMAssay Description:In vitro inhibition of specific binding of [125 I] A II to rat liver membrane.More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 813nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.55E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
3D Structure (crystal)TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 4.57E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.55E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.55E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 9.55E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 9.65E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 9.65E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 9.65E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: 9.70E+4nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Orion Pharma
Curated by ChEMBL
Orion Pharma
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Reversible inhibition of recombinant human KAT2 assessed as reduction in kynurenic acid formation using L-kynurenine as substrate by fluorescence ass...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 16nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Wyeth Research
Wyeth Research
Affinity DataEC50: 2.21E+3nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
