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Found 37 with Last Name = 'arienzo' and Initial = 'r'
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200783(ADS-103168 | CHEMBL424739 | N-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200793(ADS-103214 | CHEMBL216430 | N-(1-methyl-2-(pyrroli...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150059(CHEMBL183215 | N-(4-Methyl-2-pyrrolidin-1-yl-quino...)
Affinity DataIC50:  10nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150059(CHEMBL183215 | N-(4-Methyl-2-pyrrolidin-1-yl-quino...)
Affinity DataIC50:  10nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150059(CHEMBL183215 | N-(4-Methyl-2-pyrrolidin-1-yl-quino...)
Affinity DataIC50:  15nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  25nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200783(ADS-103168 | CHEMBL424739 | N-(2-(pyrrolidin-1-yl)...)
Affinity DataIC50:  35nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200793(ADS-103214 | CHEMBL216430 | N-(1-methyl-2-(pyrroli...)
Affinity DataIC50:  40nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200790(2-(4-methoxyphenoxy)-N-(4-methyl-2-(pyrrolidin-1-y...)
Affinity DataIC50:  41nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150063(CHEMBL364863 | N-[4-Methyl-2-(4-methyl-piperazin-1...)
Affinity DataIC50:  63nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200791(ADS-103294 | CHEMBL214678 | N-(2-(isopropylamino)-...)
Affinity DataIC50:  70nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150057(2-(4-Chloro-phenoxy)-N-[4-methyl-2-(4-methyl-piper...)
Affinity DataIC50:  71nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200792(ADS-102891 | CHEMBL424728 | N-(4-methyl-2-(pyrroli...)
Affinity DataIC50:  100nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200791(ADS-103294 | CHEMBL214678 | N-(2-(isopropylamino)-...)
Affinity DataIC50:  101nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200794(CHEMBL216407 | N-(2-(piperazin-1-ylmethyl)quinolin...)
Affinity DataIC50:  122nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150064(CHEMBL182886 | N-(4-Methyl-2-morpholin-4-yl-quinol...)
Affinity DataIC50:  124nMAssay Description:Tested for MCH-1 induced [Ca2+] release from CHO cells transfected with human MCH-1RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200785(ADS-103254 | CHEMBL217712 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  164nMAssay Description:Inhibition of MCH-mediated calcium influx into MCH-R1 expressing cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200792(ADS-102891 | CHEMBL424728 | N-(4-methyl-2-(pyrroli...)
Affinity DataIC50:  165nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200784(CHEMBL217459 | N-(2-morpholinoquinolin-6-yl)-2-(4-...)
Affinity DataIC50:  172nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150072(2-(2,3-Dichloro-phenoxy)-N-[4-methyl-2-(4-methyl-p...)
Affinity DataIC50:  201nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  250nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200785(ADS-103254 | CHEMBL217712 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  260nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150057(2-(4-Chloro-phenoxy)-N-[4-methyl-2-(4-methyl-piper...)
Affinity DataIC50:  349nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200790(2-(4-methoxyphenoxy)-N-(4-methyl-2-(pyrrolidin-1-y...)
Affinity DataIC50:  390nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150061(CHEMBL185376 | N-(2-Isopropylamino-4-methyl-quinol...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150063(CHEMBL364863 | N-[4-Methyl-2-(4-methyl-piperazin-1...)
Affinity DataIC50:  442nMAssay Description:Inhibitory activity against human 5-HT2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200789(2-(4-chlorophenoxy)-N-(2-morpholinoquinolin-6-yl)a...)
Affinity DataIC50:  961nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150057(2-(4-Chloro-phenoxy)-N-[4-methyl-2-(4-methyl-piper...)
Affinity DataIC50:  970nMAssay Description:Inhibitory activity against human 5-HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of 5HT2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200786(2-(2-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.93E+3nMAssay Description:Displacement of 125I-[Phe13,Tyr19]-MCH from MCH-R1 expressing cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50150057(2-(4-Chloro-phenoxy)-N-[4-methyl-2-(4-methyl-piper...)
Affinity DataIC50:  2.18E+3nMAssay Description:Inhibitory activity against human 5-HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of hERG in patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50241099(ADS-103274 | CHEMBL276393 | N-(2-((2-(dimethylamin...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of MCH-R2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50200788(2-(4-chlorophenoxy)-N-(4-methyl-2-(pyrrolidin-1-yl...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of D2(L)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed