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Found 35 with Last Name = 'arrington' and Initial = 'mp'
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50073179(8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-be...)
Affinity DataKi:  0.970nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155335(1-{4-[4-(3-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142873(CHEMBL53070 | {(4bS,8aR)-4b-[2-(tert-Butoxycarbony...)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155341(1-(4-{4-[3-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM22890(2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataKi:  26nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataKi:  30nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142868(CHEMBL51146 | CHEMBL540283 | {[2-((4aS,10aR)-6-Met...)
Affinity DataKi:  37nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142871(Allyl-[2-((4aS,10aR)-6-methoxy-1,3,4,10a-tetrahydr...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142866((2-Methoxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4,1...)
Affinity DataKi:  49nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155334(1-(4-{4-[4-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataKi:  50nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155339(1-{4-[4-(3-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataKi:  109nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142869(CHEMBL301772 | {(4bR,8aS)-4b-[2-(tert-Butoxycarbon...)
Affinity DataKi:  115nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142867(2-{[2-((4aS,10aR)-6-Methoxy-1,3,4,10a-tetrahydro-2...)
Affinity DataKi:  161nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142864((2-Benzyloxy-ethyl)-[2-((4aS,10aR)-6-methoxy-1,3,4...)
Affinity DataKi:  241nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142870(CHEMBL545668 | [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-...)
Affinity DataKi:  245nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataKi:  295nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155333(1-{4-[4-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataKi:  305nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50366613(DEXTROMETHORPHAN)
Affinity DataKi:  348nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142868(CHEMBL51146 | CHEMBL540283 | {[2-((4aS,10aR)-6-Met...)
Affinity DataKi:  373nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM22876(CHEMBL998 | Claritin | Loratadine | Sch 29851 | US...)
Affinity DataKi:  414nMAssay Description:Binding affinity towards human histamine H1 receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142863(CHEMBL298778 | [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-...)
Affinity DataKi:  456nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142874(CHEMBL299327 | N-{2-[(4aS,10aR)-6-methoxy-1,2,3,4,...)
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50142875(CHEMBL301487 | [2-((4aS,10aR)-6-Methoxy-1,3,4,10a-...)
Affinity DataKi: >3.30E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to Sigma receptor type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155340(1-{4-[4-(2-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataIC50:  48nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155334(1-(4-{4-[4-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataIC50:  57nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155338(1-{4-[4-(4-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataIC50:  68nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155336(1-{4-[4-(4-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataIC50:  89nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155339(1-{4-[4-(3-{4-[bis(4-fluorophenyl)methyl]piperazin...)
Affinity DataIC50:  90nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155335(1-{4-[4-(3-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataIC50:  96nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155337(1-(4-{4-[2-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataIC50:  185nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155341(1-(4-{4-[3-(4-{13-chloro-4-azatricyclo[9.4.0.0^{3,...)
Affinity DataIC50:  194nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50155333(1-{4-[4-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]...)
Affinity DataIC50:  213nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  873nMAssay Description:Inhibition of 5-lipooxygenase activity in human whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank