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Found 16 with Last Name = 'asaba' and Initial = 't'
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of human recombinant SIRT1 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human recombinant SIRT2 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant SIRT3 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human recombinant SIRT2 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM50300464((S)-benzyl 6-ethanethioamido-1-oxo-1-(phenylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant SIRT3 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Nagoya City University

Curated by ChEMBL
LigandPNGBDBM27507(3-Pyridinecarboxamide | CHEMBL1140 | NAM | niacina...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human recombinant SIRT1 after 60 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579109((R)-2-((1R,3S,5S)-3-((3S,4R)-1-(5-chloropyrimidin-...)
Affinity DataEC50:  1.40E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579109((R)-2-((1R,3S,5S)-3-((3S,4R)-1-(5-chloropyrimidin-...)
Affinity DataEC50:  4.30nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  3.90E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  2.30nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  4.70E+3nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50:  3.08nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579108(3-methoxyisonicotinonitrile | US11479552, Example ...)
Affinity DataEC50: >100nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579110((R)-2-cyclopropyl-2-((1R,3S,5S)-3-((2S, 4S)-1-(5-f...)
Affinity DataEC50:  4.40nMAssay Description:Human Embryonic Kidney cells 293 (HEK293) cells with forced expression of hOX1R or hOX2R were seeded in a 384-well microplate (Greiner) at 10,000 per...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50: >100nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Eisai R&D Management

US Patent
LigandPNGBDBM579107(2-bromo-2-cyclopropyl acetamide | US11479552, Exam...)
Affinity DataEC50:  0.990nMAssay Description:HEK293 (human embryonic kidney 293) cells with forced expression of human OX1R (hOX1R) or human OX2R (hOX2R) were seeded in a 384-well microplate (Gr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent