Compile Data Set for Download or QSAR
maximum 50k data
Found 263 with Last Name = 'ashton' and Initial = 'd'
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226415(CHEMBL3142312)
Affinity DataKi:  0.880nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50375517(CHEMBL411245)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  0.920nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  0.950nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  1.5nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  1.60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226410(CHEMBL3142318)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226412(CHEMBL3142332)
Affinity DataKi:  1.70nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226411(CHEMBL3142329)
Affinity DataKi:  1.90nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226417(CHEMBL3142331)
Affinity DataKi:  2.5nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226413(CHEMBL2369777)
Affinity DataKi:  2.60nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  2.60nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50375516(CHEMBL258759)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016752(CHEMBL339943 | N*1*-[1-(1-Carbamoyl-4-guanidino-bu...)
Affinity DataKi:  2.90nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  3.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50013515((+)-yohimbine | (16alpha,17alpha)-17-hydroxyyohimb...)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM81444(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)
Affinity DataKi:  3.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2A adrenergic receptor [16-465](Rattus norvegicus (rat))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM31046(3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphe...)
Affinity DataKi:  3.70nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  3.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226416(CHEMBL2369525)
Affinity DataKi:  3.90nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226414(CHEMBL2369778)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against sigma receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016753(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.20nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016757(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(RABBIT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  4.5nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020655(CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...)
Affinity DataKi:  4.60nMAssay Description:Tested for inhibition of [3H]-LVP binding to vasopressin receptor in medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020655(CHEMBL408474 | [6-Amino-2-({1-[19-amino-13-benzyl-...)
Affinity DataKi:  4.60nMAssay Description:Compound was tested for inhibition of hog kidney reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.70nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016747(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  4.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  4.90nMMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50375515(CHEMBL410288)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor in DDT1MF-2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(RABBIT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM81444(CAS_185453 | NSC_185453 | WB 4101 | WB-4101)
Affinity DataKi:  5.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016760(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  5.80nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016756(CHEMBL265591 | c(Pmp-D-Tyr(Et)-Phe-Val-Asn-Cys)-Pr...)
Affinity DataKi:  6nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(RABBIT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM30712(6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...)
Affinity DataKi:  6.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAlpha-2B adrenergic receptor(RABBIT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  6.40nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020653(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  6.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase (Vasopressin V2 receptor) of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016755(20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzyl)-...)
Affinity DataKi:  6.80nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney (Vasopressin V2 receptor)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2B adrenergic receptor(RABBIT)
Glaxosmithkline

Curated by PDSP Ki Database
LigandPNGBDBM50019492((+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)...)
Affinity DataKi:  7.30nMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVasopressin V2 receptor(Homo sapiens (Human))
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of human kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016763(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  7.60nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate cyclase type 4(Homo sapiens (Human))
Research And Development Division

Curated by ChEMBL
LigandPNGBDBM50226418(CHEMBL3142313)
Affinity DataKi:  7.80nMAssay Description:Binding affinity for dopamine receptor D2 was evaluated by the ability to displace [3H]spiperoneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50225877((2R,3S,4R,5R)-2-(hydroxymethyl)-5-(6-((R)-tetrahyd...)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]CPX from adenosine A1 receptor expressed in DDT1 MF2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016754(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  8.30nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020656(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020656(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Tested for inhibition of vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidney.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Sus scrofa)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50016761(1-[20-Benzyl-14-carbamoylmethyl-23-(4-ethoxy-benzy...)
Affinity DataKi:  9.40nMAssay Description:Inhibition constant for vasopressin-stimulated adenylate cyclase of medullary membranes of pig kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 263 total ) | Next | Last >>
Jump to: