TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 0.910nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia
Curated by PDSP Ki Database
University of Virginia
Curated by PDSP Ki Database
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia
Curated by PDSP Ki Database
University of Virginia
Curated by PDSP Ki Database
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 3.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.60nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 6.80nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 8.70nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 14nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 21nM ΔG°: -43.2kJ/mole IC50: 31nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 50nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 52nM ΔG°: -41.0kJ/mole IC50: 103nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
Affinity DataKi: 55nM ΔG°: -40.9kJ/mole IC50: 133nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
Affinity DataKi: 56nM ΔG°: -40.8kJ/mole IC50: 63nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
Affinity DataKi: 65nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 83nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 102nM ΔG°: -39.4kJ/mole IC50: 168nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 112nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 120nM ΔG°: -39.0kJ/mole IC50: 268nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
Affinity DataKi: 121nM ΔG°: -39.0kJ/mole IC50: 183nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Competitive inhibition of recombinant Trypanosoma cruzi cruzain by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 184nM ΔG°: -37.9kJ/mole IC50: 452nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 288nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 320nM ΔG°: -36.6kJ/mole IC50: 430nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetMelanin-concentrating hormone receptor 2(Homo sapiens (Human))
Merck Research Laboratories
Curated by PDSP Ki Database
Merck Research Laboratories
Curated by PDSP Ki Database
Affinity DataKi: 514nM ΔG°: -35.4kJ/mole IC50: 1.06E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
Affinity DataKi: 556nM ΔG°: -35.2kJ/mole IC50: 1.29E+3nMpH: 5.9 T: 2°CAssay Description:Enzyme activity was determined as the production of fluorescent resorufin from the substrate. The fluorescence was measured (excitation 570 nm, emiss...More data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 562nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 617nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 676nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia
Curated by PDSP Ki Database
University of Virginia
Curated by PDSP Ki Database
TargetParathyroid hormone/parathyroid hormone-related peptide receptor(Homo sapiens (Human))
James Black Foundation
Curated by ChEMBL
James Black Foundation
Curated by ChEMBL
Affinity DataKi: 708nMAssay Description:Displacement of [125I]-[Nle,8,18 Tyr34]-hPTH(1-34) from human recombinant PTH1R expressed in HEK293 cellsChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 795nMAssay Description:Inhibition of full length recombinant human N-terminal His8-tagged Cyclophilin A (1 to 169 residues) expressed in Escherichia coli BL21(DE3) using Su...More data for this Ligand-Target Pair