Affinity DataIC50: 0.0400nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 0.0640nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of Aurora B kinase in human HeLa Kyoto cells assessed as effect on distribution of phspho-histone H3 ser10 level incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 6.20nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of Aurora A kinase autophosphorylation at Thr288 in human HeLa Kyoto cells incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: >10nMAssay Description:Inhibition of Aurora B kinase in human HeLa Kyoto cells assessed as effect on distribution of phspho-histone H3 ser10 level incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of Aurora A kinase autophosphorylation at Thr288 in human HeLa Kyoto cells incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of Aurora A kinase autophosphorylation at Thr288 in human HeLa Kyoto cells incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 370nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of Flag-tagged TRPM4 (unknown origin) expressed in HEK293 cells assessed as reduction in intracellular Na+ influx after 45 mins by ANG2 dy...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 760nMAssay Description:Inhibition of Aurora A kinase autophosphorylation at Thr288 in human HeLa Kyoto cells incubated for 20 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Flag-tagged TRPM4 (unknown origin) expressed in HEK293 cells assessed as reduction in intracellular Na+ influx after 45 mins by ANG2 dy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Flag-tagged TRPM4 (unknown origin) expressed in HEK293 cells assessed as reduction in intracellular Na+ influx after 45 mins by ANG2 dy...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Flag-tagged TRPM4 (unknown origin) expressed in HEK293 cells assessed as reduction in intracellular Na+ influx after 45 mins by ANG2 dy...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetAurora kinase B/Inner centromere protein(Homo sapiens (Human))
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of Aurora-B/INCENP (unknown origin) using biotinylated STK2 substrate incubated for 30 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily M member 4(Homo sapiens)
University Of Berne
Curated by ChEMBL
University Of Berne
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Flag-tagged TRPM4 (unknown origin) expressed in HEK293 cells assessed as reduction in intracellular Na+ influx after 45 mins by ANG2 dy...More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of His-tagged human Aurora A kinase (122 to 40 residues) expressed in Escherichia coli BL21 (DE3) Rosetta cells using biotinylated STK2 su...More data for this Ligand-Target Pair