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Found 69 with Last Name = 'balachandran' and Initial = 's'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50262025(3-(6-(2,4-difluorophenylamino)-1H-pyrazolo[3,4-b]p...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50214095(CHEMBL248713 | CHEMBL511394 | N-((5-(3-(5-fluoro-1...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM5768((4-butoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)(phenyl)m...)
Affinity DataIC50:  110nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298023(2-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  500nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298023(2-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  800nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298023(2-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298024(2-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298024(2-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298009(CHEMBL559125 | N-cyclohexyl-3(3-(3-(3-fluoro-4-met...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298027(2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298025(1-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(CHEMBL549864 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298014(3-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298019(CHEMBL556445 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298025(1-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298013(5-(2,3-dimethoxyphenyl)-3-(3-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298019(CHEMBL556445 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(CHEMBL549864 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298010(CHEMBL559258 | N-cyclohexyl-3-(3-(3-(3-fluoro-4-hy...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(CHEMBL549864 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298019(CHEMBL556445 | N-(2-(3-(3-fluoro-4-hydroxyphenyl)-...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298022(2-((3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxaz...)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298009(CHEMBL559125 | N-cyclohexyl-3(3-(3-(3-fluoro-4-met...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298013(5-(2,3-dimethoxyphenyl)-3-(3-(3-fluoro-4-methoxyph...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298022(2-((3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxaz...)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298027(2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50:  4.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298011(CHEMBL563301 | methyl 3-(3-(3(3-fluoro-4hydroxyphe...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298025(1-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298026(3-((3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisoxaz...)
Affinity DataIC50:  5.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298007(2-fluoro-4-(5-(5-(trifluoromethyl)-1,2,4-oxadiazol...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298027(2-fluoro-4-(5((5-(trifluoromethyl)-1,2,4-oxadiazol...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298005(2-fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298006(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisoxazo...)
Affinity DataIC50:  9.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298020(2,2,2-trifluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298014(3-(3-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298011(CHEMBL563301 | methyl 3-(3-(3(3-fluoro-4hydroxyphe...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298010(CHEMBL559258 | N-cyclohexyl-3-(3-(3-(3-fluoro-4-hy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298008(3-(3-(3-(3-fluoro-4-methoxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298007(2-fluoro-4-(5-(5-(trifluoromethyl)-1,2,4-oxadiazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298005(2-fluoro-4-(5-(5-methyl-1,2,4-oxadiazol-3-yl)-4,5-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50186426(CHEMBL210858 | US10336721, ISO-1 | US10968198, ISO...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
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