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Found 40 with Last Name = 'balakin' and Initial = 'kv'
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10246((4S)-4-{[(1S)-1-{[(2S)-1-carboxy-3-oxopropan-2-yl]...)
Affinity DataIC50:  3.10nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10358(2-[7-methyl-12-(morpholine-4-sulfonyl)-3,5-dioxo-4...)
Affinity DataIC50:  23nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10360(2-[12-(morpholine-4-sulfonyl)-3,5-dioxo-7-phenyl-4...)
Affinity DataIC50:  27nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10362(2-[12-(morpholine-4-sulfonyl)-3,5-dioxo-7-[(E)-2-[...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10374(2-[12-(morpholine-4-sulfonyl)-3,5-dioxo-7-(pyridin...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10373(2-[7-(3-chloro-4-fluorophenyl)-12-(morpholine-4-su...)
Affinity DataIC50:  33nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10361(2-[7-(furan-2-yl)-12-(morpholine-4-sulfonyl)-3,5-d...)
Affinity DataIC50:  36nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10359(2-[12-(morpholine-4-sulfonyl)-3,5-dioxo-7-(propan-...)
Affinity DataIC50:  40nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10372(2-{7-[4-(dimethylcarbamoyl)phenyl]-12-(morpholine-...)
Affinity DataIC50:  58nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10365(pyrrolo[3,4-c]-quinoline-1,3-dione 21a)
Affinity DataIC50:  255nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10364(2-[7-chloro-12-(morpholine-4-sulfonyl)-3,5-dioxo-4...)
Affinity DataIC50:  294nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10370(methyl 2-({4-[2-(acetyloxy)ethyl]-12-(morpholine-4...)
Affinity DataIC50:  352nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10371(methyl 2-({4-[2-(acetyloxy)ethyl]-12-(morpholine-4...)
Affinity DataIC50:  362nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189893(CHEMBL3828679)
Affinity DataIC50:  460nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189893(CHEMBL3828679)
Affinity DataIC50:  590nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50313079(3-Dimethylcarbamoyloxy-1-methyl-pyridinium; bromid...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10366(methyl 2-({4-[2-(acetyloxy)ethyl]-12-(morpholine-4...)
Affinity DataIC50:  1.29E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189894(CHEMBL3827011)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189894(CHEMBL3827011)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189895(CHEMBL3828028)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10368(1,4-diethyl (2R)-2-({4-[2-(acetyloxy)ethyl]-12-(mo...)
Affinity DataIC50:  5.19E+3nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189895(CHEMBL3828028)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10363(2-[7-hydroxy-12-(morpholine-4-sulfonyl)-3,5-dioxo-...)
Affinity DataIC50:  1.09E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10367(2-[7-(morpholin-4-yl)-12-(morpholine-4-sulfonyl)-3...)
Affinity DataIC50:  1.54E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Chemical Diversity Research Institute

LigandPNGBDBM10369(2-{7-[(3-chloro-4-fluorophenyl)amino]-12-(morpholi...)
Affinity DataIC50:  2.79E+4nMpH: 7.5 T: 2°CAssay Description:The substrate peptides terminating in AMC are processed by caspases with or without inhibitors. The amount of AMC released was determined by using a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189896(CHEMBL3827624)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189892(CHEMBL3827856)
Affinity DataIC50:  1.30E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189888(CHEMBL3827449)
Affinity DataIC50:  1.40E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189891(CHEMBL3828644)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189887(CHEMBL3827347)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189889(CHEMBL3828273)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189896(CHEMBL3827624)
Affinity DataIC50:  3.10E+5nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189888(CHEMBL3827449)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189892(CHEMBL3827856)
Affinity DataIC50:  4.00E+5nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189890(CHEMBL3828739)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibition of human AChE assessed as acetylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189889(CHEMBL3828273)
Affinity DataIC50:  8.00E+5nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189887(CHEMBL3827347)
Affinity DataIC50:  9.00E+5nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189891(CHEMBL3828644)
Affinity DataIC50:  1.03E+6nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Kazan (Volga Region) Federal University

Curated by ChEMBL
LigandPNGBDBM50189890(CHEMBL3828739)
Affinity DataIC50:  1.19E+6nMAssay Description:Inhibition of human plasma BChE assessed as butyrylthiocholine hydrolysis preincubated for 10 mins followed by addition of substrate measured after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed