Compile Data Set for Download or QSAR
maximum 50k data
Found 27 with Last Name = 'baringhaus' and Initial = 'k'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142068(US8933024, 46)
Affinity DataIC50:  28nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142060(US8933024, 4)
Affinity DataIC50:  40nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142062(US8933024, 18)
Affinity DataIC50:  69nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142080(US8933024, 161)
Affinity DataIC50:  80nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142076(US8933024, 130)
Affinity DataIC50:  85nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142063(US8933024, 28)
Affinity DataIC50:  107nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142070(US8933024, 55)
Affinity DataIC50:  116nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142067(US8933024, 39)
Affinity DataIC50:  120nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142069(US8933024, 50)
Affinity DataIC50:  138nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142065(US8933024, 37)
Affinity DataIC50:  148nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142066(US8933024, 38)
Affinity DataIC50:  182nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142061(US8933024, 5)
Affinity DataIC50:  200nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50037255((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)
Affinity DataIC50:  200nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142072(US8933024, 114)
Affinity DataIC50:  216nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142075(US8933024, 129)
Affinity DataIC50:  230nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142071(US8933024, 59)
Affinity DataIC50:  264nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142077(US8933024, 134)
Affinity DataIC50:  391nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142078(US8933024, 142)
Affinity DataIC50:  517nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50037257((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)
Affinity DataIC50:  650nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142059(US8933024, 3)
Affinity DataIC50:  926nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50037254((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)
Affinity DataIC50:  1.00E+3nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142073(US8933024, 115)
Affinity DataIC50:  1.38E+3nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142079(US8933024, 156)
Affinity DataIC50:  1.58E+3nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142074(US8933024, 116)
Affinity DataIC50:  1.59E+3nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEndothelial lipase(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM142064(US8933024, 29)
Affinity DataIC50:  4.29E+3nMAssay Description:For characterization of the enzymatic activity of endothelial lipase and the effect of inhibitors, the phospholipase-specific substrate 1,2-bis(4,4-d...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Hoechst

Curated by ChEMBL
LigandPNGBDBM50037256((S)-2-Methyl-butyric acid (3R,5R,8R,9S,10S,12S,13R...)
Affinity DataIC50:  7.00E+3nMAssay Description:Tested for inhibition of rat liver microsomal HMG-CoA reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed