Compile Data Set for Download or QSAR
maximum 50k data
Found 65 with Last Name = 'baron' and Initial = 'l'
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332633(CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...)
Affinity DataKi:  600nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332634(CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...)
Affinity DataKi:  800nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332632(CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332631(CHEMBL1630804 | N-(4-Fluorophenyl)-7-oxo-7,7a-dihy...)
Affinity DataKi:  6.60E+3nMAssay Description:Binding affinity to GFP tagged human mGluR2 containing truncated N-terminal region expressed in HEK cells by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332632(CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...)
Affinity DataIC50:  800nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332634(CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...)
Affinity DataIC50:  1.00E+3nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332633(CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...)
Affinity DataIC50:  1.50E+3nMAssay Description:Negative allosteric modulator activity at human mGluR2 expressed in HEK cells in presence of glutamate EC80 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332632(CHEMBL1630805 | N-(4-Chlorophenyl)-7-oxo-7,7a-dihy...)
Affinity DataEC50:  1.34E+4nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332633(CHEMBL1630806 | N-(4-Methylphenyl)-7-oxo-7,7a-dihy...)
Affinity DataEC50:  8.90E+3nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Homo sapiens (Human))
Domain Therapeutics

Curated by ChEMBL
LigandPNGBDBM50332634(CHEMBL1630807 | N-(4-Methoxyphenyl)-7-oxo-7,7a-dih...)
Affinity DataEC50:  1.04E+4nMAssay Description:Positive allosteric modulator activity at human mGluR3 expressed in HEK cells in presence of glutamate EC10 concentration by Ca2+ functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.25E+3nMAssay Description:Inhibitory activity against human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50116514(CHEMBL507522)
Affinity DataEC50:  2.50E+3nMAssay Description:The compound was tested for the inhibition of human immunodeficiency virus-1 reverse transcriptase(HIV-1 RT).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241541(CHEMBL4087749)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241542(CHEMBL4065348)
Affinity DataEC50: >3.00E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241543(CHEMBL4060429)
Affinity DataEC50:  3.96E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241544(CHEMBL4081595)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241545(CHEMBL4059644)
Affinity DataEC50:  1.27E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241546(CHEMBL4071024)
Affinity DataEC50:  240nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241547(CHEMBL4097178)
Affinity DataEC50:  130nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241548(CHEMBL4089473)
Affinity DataEC50:  280nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241549(CHEMBL4068295)
Affinity DataEC50:  860nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241550(CHEMBL4067271)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241551(CHEMBL4088412)
Affinity DataEC50:  2.47E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241552(CHEMBL4085101)
Affinity DataEC50:  90nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241554(CHEMBL4063474)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241555(CHEMBL4062968)
Affinity DataEC50:  160nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241556(CHEMBL4083118)
Affinity DataEC50:  1.74E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241557(CHEMBL4101095)
Affinity DataEC50:  3.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241559(CHEMBL4093353)
Affinity DataEC50:  9.84E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241560(CHEMBL4064041)
Affinity DataEC50:  750nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241561(CHEMBL4085608)
Affinity DataEC50:  1.01E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241562(CHEMBL4103895)
Affinity DataEC50:  1.72E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241563(CHEMBL4085967)
Affinity DataEC50:  1.39E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241564(CHEMBL4096136)
Affinity DataEC50:  690nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241565(CHEMBL4082167)
Affinity DataEC50:  106nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241566(CHEMBL4100168)
Affinity DataEC50:  25nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241567(CHEMBL4072094)
Affinity DataEC50:  50nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241568(CHEMBL4100586)
Affinity DataEC50:  35nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241569(CHEMBL4062426)
Affinity DataEC50:  165nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241573(CHEMBL4098112)
Affinity DataEC50:  1.71E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241574(CHEMBL4071064)
Affinity DataEC50:  2.34E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  46nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  70nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing chimeric G protein assessed as increase in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241575(CHEMBL4067875)
Affinity DataEC50:  27nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241576(CHEMBL4061970)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241577(CHEMBL4070594)
Affinity DataEC50:  4nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241578(CHEMBL4105462)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241579(CHEMBL4081211)
Affinity DataEC50:  53nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  79nMAssay Description:Positive allosteric modulation of recombinant human mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rattus norvegicus (Rat))
Prexton Therapeutics

Curated by ChEMBL
LigandPNGBDBM50241580(CHEMBL4089083)
Affinity DataEC50:  47nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co-expressing Gi/Gq assessed as increase in glutamate-induced calcium ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 65 total ) | Next | Last >>
Jump to: