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Found 29 with Last Name = 'barrett' and Initial = 'ja'
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265453((S)-2-(3-((S)-1-Carboxy-5-(3-(4-bromophenyl)ureido...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265381((S)-2-(3-((S)-1-Carboxy-5-(4-chlorobenzylamino)pen...)
Affinity DataIC50:  2nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265471((S)-2-(3-((S)-1-Carboxy-5-(3-(4-fluorophenyl)ureid...)
Affinity DataIC50:  3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265454((S)-2-(3-((S)-1-Carboxy-5-(3-(4-chlorophenyl)ureid...)
Affinity DataIC50:  4nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291574(2-[11-[3-amino(imino)methylaminopropyl]-19-(5-amin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291570(CHEMBL367058 | DMP-757 | [11-(3-Guanidino-propyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291566(CHEMBL268350 | Hydrazinonicotinyl analogue)
Affinity DataIC50:  8nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291572(CHEMBL386693 | Hydrazinonicotinyl analogue)
Affinity DataIC50:  9nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265474((S)-2-(3-((S)-1-Carboxy-5-(4-iodophenylsulfonamido...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265783((S)-2-(3-((S)-1-Carboxy-5-(3-(4-iodophenyl)ureido)...)
Affinity DataIC50:  10nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291569(CHEMBL386694 | Hydrazinonicotinyl analogue)
Affinity DataIC50:  11nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265472((S)-2-(3-((S)-1-Carboxy-5-(3-phenylureido)pentyl)u...)
Affinity DataIC50:  12nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291567(CHEMBL384194 | Hydrazinonicotinyl analogue)
Affinity DataIC50:  13nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50366493(CHEMBL611722 | RP-444)
Affinity DataIC50:  13nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291571(CHEMBL262549 | Hydrazinonicotinyl analogue)
Affinity DataIC50:  16nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265473((9S,13S)-1-(3-iodophenyl)-3,11-dioxo-2,4,10,12-tet...)
Affinity DataIC50:  18nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265377((S)-2-(3-((S)-1-Carboxy-5-(4-iodobenzylamino)penty...)
Affinity DataIC50:  22nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265378((S)-2-(3-((S)-1-Carboxy-5-(2-iodobenzylamino)penty...)
Affinity DataIC50:  37nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265380((S)-2-(3-((S)-1-Carboxy-5-(4-bromobenzylamino)pent...)
Affinity DataIC50:  43nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265489((S)-2-(3-((S)-1-Carboxy-5-(naphthalen-1-ylmethylam...)
Affinity DataIC50:  154nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265391((S)-2-(3-((S)-1-Carboxy-5-(2-chlorobenzylamino)pen...)
Affinity DataIC50:  245nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265451((S)-2-(3-((S)-1-Carboxy-5-(3-chlorobenzylamino)pen...)
Affinity DataIC50:  277nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265379((S)-2-(3-((S)-1-Carboxy-5-(3-iodobenzylamino)penty...)
Affinity DataIC50:  443nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265784((S)-2-(3-((S)-5-Amino-1-carboxypentyl)ureido)penta...)
Affinity DataIC50:  498nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291573(CHEMBL411753 | Hydrazinonicotinyl analogue)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265452((S)-2-(3-((S)-1-Carboxy-5-(4-fluorobenzylamino)pen...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265782((S)-2-(3-((S)-5-(Benzylamino)-1-carboxypentyl)urei...)
Affinity DataIC50:  2.96E+3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate carboxypeptidase 2(Homo sapiens (Human))
Molecular Insight Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50265785((S)-2-(3-(4-iodobenzyl)ureido)pentanedioic acid | ...)
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of [131I]DCIT from PSMA in human LNCAP cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50241180((6S,12S,15S)-1,6-diamino-12-(carboxymethyl)-16-hyd...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of 125I-fibrinogen binding to alpha IIb beta-3 integrin as inhibition of activated plateletsMore data for this Ligand-Target Pair
In DepthDetails Article