Compile Data Set for Download or QSAR
maximum 50k data
Found 369 with Last Name = 'barton' and Initial = 'l'
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078697(CHEMBL54138 | {(S)-7-[2-(1H-Imidazol-2-ylamino)-et...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054826(CHEMBL144474 | [7-([4,4']Bipiperidinyl-1-carbonyl)...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078696(CHEMBL52026 | {(S)-7-[(2-Amino-3H-imidazol-4-ylmet...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078710(CHEMBL298782 | {(S)-7-[2-(6-Amino-pyridin-2-ylamin...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059133(CHEMBL50106 | SB-223245 | {(S)-7-[(1H-Benzoimidazo...)
Affinity DataKi:  2nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054830(CHEMBL356986 | [(R)-7-([4,4']Bipiperidinyl-1-carbo...)
Affinity DataKi:  2.5nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036088(CHEMBL18734 | [(6S,13S)-13-(3-Guanidino-propyl)-14...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078703(CHEMBL301760 | {(S)-4-Methyl-3-oxo-7-[2-(pyridin-2...)
Affinity DataKi:  3.5nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054831(CHEMBL143219 | [7-([4,4']Bipiperidinyl-1-carbonyl)...)
Affinity DataKi:  4nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054824(CHEMBL144681 | {7-[Methyl-(3-piperidin-4-yl-propyl...)
Affinity DataKi:  8nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078705(CHEMBL299591 | {(S)-7-[(6-Ethylamino-pyridin-2-ylm...)
Affinity DataKi:  9nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078698(CHEMBL296615 | {(S)-4-Methyl-7-[methyl-(6-methylam...)
Affinity DataKi:  11nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054829(CHEMBL306110 | [7-(3-Carbamimidoyl-phenylcarbamoyl...)
Affinity DataKi:  26nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078706(CHEMBL52681 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  28nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078704(((S)-4-Methyl-7-{methyl-[2-(pyridin-2-ylamino)-eth...)
Affinity DataKi:  33nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078712(CHEMBL50028 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  35nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078711(CHEMBL50257 | {(S)-7-[2-(6-Amino-pyridin-2-yl)-eth...)
Affinity DataKi:  85nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054828(CHEMBL143394 | {7-[(3-Carbamimidoyl-phenyl)-methyl...)
Affinity DataKi:  90nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078701(CHEMBL50510 | [(S)-7-(6-Amino-pyridin-2-ylcarbamoy...)
Affinity DataKi:  150nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078707(CHEMBL53987 | {(S)-4-Methyl-7-[2-(6-methyl-pyridin...)
Affinity DataKi:  280nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078709(CHEMBL53985 | {(S)-7-[(3H-Imidazol-4-ylmethyl)-car...)
Affinity DataKi:  490nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078696(CHEMBL52026 | {(S)-7-[(2-Amino-3H-imidazol-4-ylmet...)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078700(CHEMBL417014 | [(S)-4-Methyl-3-oxo-7-(4-pyridin-2-...)
Affinity DataKi:  1.25E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50054825(CHEMBL356301 | [(S)-7-([4,4']Bipiperidinyl-1-carbo...)
Affinity DataKi:  1.53E+3nMAssay Description:Inhibition of binding to purified integrin alphaIIb-beta3 of human plateletsMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078707(CHEMBL53987 | {(S)-4-Methyl-7-[2-(6-methyl-pyridin...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078708(CHEMBL53725 | {(S)-4-Methyl-3-oxo-7-[2-(pyrimidin-...)
Affinity DataKi:  3.00E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078698(CHEMBL296615 | {(S)-4-Methyl-7-[methyl-(6-methylam...)
Affinity DataKi:  3.65E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078710(CHEMBL298782 | {(S)-7-[2-(6-Amino-pyridin-2-ylamin...)
Affinity DataKi:  5.00E+3nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078702(CHEMBL300412 | {(S)-4-Methyl-3-oxo-7-[(pyridin-2-y...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078706(CHEMBL52681 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078697(CHEMBL54138 | {(S)-7-[2-(1H-Imidazol-2-ylamino)-et...)
Affinity DataKi:  8.20E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078711(CHEMBL50257 | {(S)-7-[2-(6-Amino-pyridin-2-yl)-eth...)
Affinity DataKi:  8.50E+3nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078709(CHEMBL53985 | {(S)-7-[(3H-Imidazol-4-ylmethyl)-car...)
Affinity DataKi:  1.10E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078705(CHEMBL299591 | {(S)-7-[(6-Ethylamino-pyridin-2-ylm...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078704(((S)-4-Methyl-7-{methyl-[2-(pyridin-2-ylamino)-eth...)
Affinity DataKi:  2.00E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078699(CHEMBL50075 | [(S)-4-Methyl-3-oxo-7-(2-phenylamino...)
Affinity DataKi:  2.20E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078703(CHEMBL301760 | {(S)-4-Methyl-3-oxo-7-[2-(pyridin-2...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50059133(CHEMBL50106 | SB-223245 | {(S)-7-[(1H-Benzoimidazo...)
Affinity DataKi:  3.00E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078712(CHEMBL50028 | {(S)-7-[(6-Amino-pyridin-2-ylmethyl)...)
Affinity DataKi:  3.20E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078700(CHEMBL417014 | [(S)-4-Methyl-3-oxo-7-(4-pyridin-2-...)
Affinity DataKi:  4.05E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078702(CHEMBL300412 | {(S)-4-Methyl-3-oxo-7-[(pyridin-2-y...)
Affinity DataKi:  4.15E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078708(CHEMBL53725 | {(S)-4-Methyl-3-oxo-7-[2-(pyrimidin-...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human alpha IIb beta3 integrin by [3H]-RGD peptide displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078699(CHEMBL50075 | [(S)-4-Methyl-3-oxo-7-(2-phenylamino...)
Affinity DataKi: >5.00E+4nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50078701(CHEMBL50510 | [(S)-7-(6-Amino-pyridin-2-ylcarbamoy...)
Affinity DataKi:  1.60E+5nMAssay Description:Binding affinity towards human Vitronectin receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607602(CHEMBL5220994)
Affinity DataIC50:  0.0794nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607596(CHEMBL5221053)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607597(CHEMBL5219157)
Affinity DataIC50:  0.126nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone acetyltransferase p300(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50607595(CHEMBL5219030)
Affinity DataIC50:  0.158nMAssay Description:Inhibition of full-length P300 (unknown origin) using ARTKQTARKSTGGKAPRKQLAGG-K(Biotin)-amide as substrate preincubated for 60 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Displayed 1 to 50 (of 369 total ) | Next | Last >>
Jump to: