Affinity DataKi: 0.240nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 69nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 147nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 227nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 500nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 615nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 700nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 870nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 873nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.17E+3nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.00E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 1.60E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 4.90E+4nMAssay Description:Displacement of [leucine-3H]NT (8 to 13 residues) from human NTS2 receptor expressed in HEK293 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 6.70E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.05E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.25E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 7.25E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.23E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 9.23E+4nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]neurotensin from human NTS1 receptor expressed in CHOK1 cell membranes after 60 mins by scintillation countingMore data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Binding affinity to MTH1 in human K562 cells assessed as concentration required to achieve half of the maximal stabilization of protein at 54 degC af...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
Sprint Bioscience
Curated by ChEMBL
Sprint Bioscience
Curated by ChEMBL
Affinity DataIC50: <0.100nMAssay Description:Inhibition of human full length MTH1 using 8-Oxo-2-dGTP as substrate preincubated for 15 mins followed substrate addition measured after 1 hr by PPil...More data for this Ligand-Target Pair