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Found 55 with Last Name = 'baxter' and Initial = 'jd'
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)
Affinity DataIC50:  370nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataIC50:  680nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)
Affinity DataIC50:  950nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha1 (hTRalpha1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha1 (hTRalpha1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM35905(Tolfenamic acid | cid_610479 | flufenamic acid ana...)
Affinity DataIC50:  4.70E+4nMAssay Description:Activity at androgen receptor ligand binding domain assessed as inhibition of SRC2-3 interaction after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105667(CHEMBL98135 | {4-[4-Hydroxy-1-(4-hydroxy-3-isoprop...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105668(CHEMBL264527 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  240nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105669(CHEMBL97613 | {4-[1-(4-Hydroxy-3-isopropyl-phenyl)...)
Affinity DataKd:  90nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105670(CHEMBL318132 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  148nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.170nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105668(CHEMBL264527 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  720nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.140nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105670(CHEMBL318132 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  112nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105671(CHEMBL97187 | {4-[(2,4-Dimethoxy-phenyl)-(4-hydrox...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105667(CHEMBL98135 | {4-[4-Hydroxy-1-(4-hydroxy-3-isoprop...)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105671(CHEMBL97187 | {4-[(2,4-Dimethoxy-phenyl)-(4-hydrox...)
Affinity DataKd:  4.20E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR beta 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50105669(CHEMBL97613 | {4-[1-(4-Hydroxy-3-isopropyl-phenyl)...)
Affinity DataKd:  430nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataKd:  200nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115666(CHEMBL109430 | {4-[4-Hydroxy-3-isopropyl-5-(4-pent...)
Affinity DataKd:  5.20nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataKd:  35nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataKd:  490nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)
Affinity DataKd:  20nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  1.80nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115669(CHEMBL110158 | {4-[3-(4-Amino-phenylethynyl)-4-hyd...)
Affinity DataKd:  330nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  2nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115666(CHEMBL109430 | {4-[4-Hydroxy-3-isopropyl-5-(4-pent...)
Affinity DataKd:  0.520nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataEC50:  7nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115666(CHEMBL109430 | {4-[4-Hydroxy-3-isopropyl-5-(4-pent...)
Affinity DataEC50:  380nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataKd:  37nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataEC50:  45nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha1 (hTRalpha1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataEC50:  2nMAssay Description:Half-maximum activation of human Thyroid hormone receptor alpha1 (hTRalpha1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)
Affinity DataKd:  93nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataEC50:  500nMAssay Description:Half-maximum activation of human Thyroid hormone receptor beta 1 (hTRbeta1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115669(CHEMBL110158 | {4-[3-(4-Amino-phenylethynyl)-4-hyd...)
Affinity DataKd:  90nMAssay Description:Binding affinity against human Thyroid hormone receptor beta 1 (hTRbeta1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130594(3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-p...)
Affinity DataKd:  0.220nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0870nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  8.5nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130597(2-Amino-3-[4-(4-hydroxy-3-isopropyl-benzyl)-3,5-di...)
Affinity DataKd:  1.26nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130596(CHEMBL419016 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataKd:  0.360nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130594(3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-p...)
Affinity DataKd:  0.690nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130596(CHEMBL419016 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130597(2-Amino-3-[4-(4-hydroxy-3-isopropyl-benzyl)-3,5-di...)
Affinity DataKd:  2.02nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  0.660nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  9.80nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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