TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxinMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of NADPHMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 650nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of thioredoxinMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to Plasmodium falciparum TrxR in presence of NADPHMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 4.10nMAssay Description:Inhibitory concentration against human glutathione reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
Affinity DataIC50: 190nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Plasmodium falciparum TrxRMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMpH: 7.5Assay Description:An AR-response element is contained within the mmTV sequence and drives the expression of luciferase. The effect of antiandrogens (competitive antago...More data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.94E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum TrxRMore data for this Ligand-Target Pair
TargetThioredoxin reductase(Plasmodium falciparum (isolate 3D7))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Plasmodium falciparum TrxRMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic/2, mitochondrial/3(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human TrxRMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.06E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.35E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.39E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.53E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:In vitro inhibition of human Glutathione ReductaseMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
Affinity DataIC50: 3.28E+3nMpH: 7.5Assay Description:Briefly, the AR LBD is expressed as a fusion with the Gal4 transcription factor, which binds to the Gal4 reporter DNA. Upon activation with agonist h...More data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetThioredoxin reductase 1, cytoplasmic/2, mitochondrial/3(Homo sapiens (Human))
University Of Michigan
Curated by ChEMBL
University Of Michigan
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human TrxRMore data for this Ligand-Target Pair
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Umr 8525 Cnrs-Université
Curated by ChEMBL
Umr 8525 Cnrs-Université
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:In vitro inhibition of Plasmodium falciparum Glutathione ReductaseMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 4.13E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair