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Found 267 with Last Name = 'beier' and Initial = 'n'
TargetType-2 angiotensin II receptor(RAT)
E. Merck

Curated by ChEMBL
LigandPNGBDBM50041700(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataKi:  300nMAssay Description:Binding affinity against angiotensin II receptor type 2 (AT2) of rat adrenal medulla.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50242614((S)-1-((S)-2-((S)-2,5-diamino-5-oxopentanamido)-3-...)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake after 1 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50242617(CHEMBL521026 | QSPac)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake after 1 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285171(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)
Affinity DataIC50:  0.650nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285833(1N,1N-dimethyl-2-(2-butyl-4-oxo-3-{4-[2-(1H-1,2,3,...)
Affinity DataIC50:  0.700nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50041701(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  1.10nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50041688(CHEMBL43500 | {2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-...)
Affinity DataIC50:  1.30nMAssay Description:Binding affinity against AT1 receptor of rat adrenal cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285164(1-Cyclohexyl-3-(2-{2,6-dioxo-4-propyl-3-[2'-(1H-te...)
Affinity DataIC50:  1.40nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50406795(Cozaar | LOSARTAN POTASSIUM)
Affinity DataIC50:  1.5nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50041689(5-Benzyl-2-butyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  1.70nMAssay Description:Binding affinity against AT1 receptor of rat adrenal cortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50242615(CHEMBL486028 | QCPac)
Affinity DataIC50:  2nMAssay Description:Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake after 1 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403246(CHEMBL2079787)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50471224(CHEMBL64889)
Affinity DataIC50:  2nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403242(CHEMBL2079790)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282613(6-{2-Cyclopropyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403247(CHEMBL2079791)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403245(CHEMBL2079788)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/glucose cotransporter 1(Homo sapiens (Human))
University WüRzburg

Curated by ChEMBL
LigandPNGBDBM50242616(CHEMBL485831 | QCP)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of human SGLT1 expressed in xenopus laevis oocyte assessed as inhibition of methyl-alpha-D-[14C]glucopyranoside uptake after 1 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285165(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-bip...)
Affinity DataIC50:  2.30nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285163(2-{4-Butyl-2,6-dioxo-3-[2'-(1H-tetrazol-5-yl)-biph...)
Affinity DataIC50:  2.40nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285818(2-Butyl-5-(2-morpholin-4-yl-2-oxo-1-phenyl-ethyl)-...)
Affinity DataIC50:  2.90nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282616(6-{2-Cyclopropyl-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM82258(CAS_114798-26-4 | Losartan | NSC_3961)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285832(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  3nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50041683(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  3nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403243(CHEMBL2079789)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285820(CHEMBL88663 | {2-Ethyl-4-oxo-3-[2'-(1H-tetrazol-5-...)
Affinity DataIC50:  3.10nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285829(CHEMBL314603 | {4-Oxo-2-propyl-3-[2'-(1H-tetrazol-...)
Affinity DataIC50:  3.10nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285166(3-Allyl-6-propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  3.30nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285160(CHEMBL292781 | N-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-...)
Affinity DataIC50:  3.40nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285834(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  3.60nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50450370(CHEMBL313691)
Affinity DataIC50:  3.70nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50403244(CHEMBL2079785)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50282611((3-{2-Cyclopropyl-3-[2'-(1H-tetrazol-5-yl)-bipheny...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Angiotensin II receptor, type 1 induced contractions in isolated rabbit aortic ringsMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285813(CHEMBL316063 | {2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5...)
Affinity DataIC50:  4nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285821(2-Butyl-5-(2-oxo-1-phenyl-propyl)-3-[2'-(1H-tetraz...)
Affinity DataIC50:  4.10nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285816(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  4.20nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285177(6-Propyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  4.30nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285835(2-Butyl-5-(2-oxo-1-phenyl-2-piperidin-1-yl-ethyl)-...)
Affinity DataIC50:  4.40nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50285173(2-(2-{2,6-Dioxo-4-propyl-3-[2'-(1H-tetrazol-5-yl)-...)
Affinity DataIC50:  4.40nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285167(6-Butyl-3-methyl-1-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  4.5nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50471235(CHEMBL416314)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50041676(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  5.30nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285826(2-{2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-yl)-biphenyl...)
Affinity DataIC50:  5.60nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50471210(CHEMBL292311)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50471144(CHEMBL60551)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium/hydrogen exchanger 3(Oryctolagus cuniculus)
Merck

Curated by ChEMBL
LigandPNGBDBM50471218(CHEMBL59697)
Affinity DataIC50:  6nMAssay Description:Inhibition of 5-N-(ethyl isopropyl)-amiloride[EIPA]-sensitive Na+ uptake into acidified rabbit erythrocytes.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50285175(7-Propyl-6-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)
Affinity DataIC50:  6.20nMAssay Description:Tested for binding affinity against angiotensin II receptor in rat adrenal cortexMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285814(CHEMBL88170 | {2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5-...)
Affinity DataIC50:  6.5nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285822(CHEMBL420607 | {2-Butyl-4-oxo-3-[2'-(1H-tetrazol-5...)
Affinity DataIC50:  6.5nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
In DepthDetails Article
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