TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
The Netherlands Cancer Institute
Curated by ChEMBL
The Netherlands Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of MTX uptake in membrane vesicle from BCRP-expressing Sf9 cellMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
The Netherlands Cancer Institute
Curated by ChEMBL
The Netherlands Cancer Institute
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of PMEA efflux (PMEA: 1 uM) in MRP5-expressing MDCKII cellsMore data for this Ligand-Target Pair