Affinity DataKi: 0.600nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 0.800nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of factor 10a using bis-(CBZ-glycylglycly)-L-arginine amide fluorogenic substrateMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0360nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0470nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.690nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 0.880nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Binding affinity for dopamine D4-like receptor labelled with [3H]YM-09151-2 in retinaMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastase at a concentration of 10 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Opioid receptor kappa 1 agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: >10nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Kappa-opioid receptor agonist potency of the compound was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 0 min.More data for this Ligand-Target Pair
Affinity DataIC50: 29nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:In vitro inhibitory activity against human neutrophil elastase (HNE)More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
Affinity DataIC50: 46nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 40 min.More data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Opioid receptor kappa agonist potency was determined in vitro using rabbit vas deferens(LVD) preparationMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Homo sapiens (Human))
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Glaxowellcome Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:The compound was tested for inhibition of human neutrophil elastase enzyme with a preincubation time of 15 min.More data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Opioid receptor kappa 1 agonist potency was determined in vitro using rabbit vas deferens (LVD) preparationMore data for this Ligand-Target Pair