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Found 128 with Last Name = 'bence' and Initial = 'nf'
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575632(US11464802, Compound 1)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575633(US11464802, Compound 2)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575641(US11464802, Compound 10)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575659(US11464802, Compound 22)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575660(US11464802, Compound 23)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575661(US11464802, Compound 24)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575669(US11464802, Compound 32)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575673(US11464802, Compound 36)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575676(US11464802, Compound 39)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575677(US11464802, Compound 40)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575681(US11464802, Compound 44)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575685(US11464802, Compound 49)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575686(US11464802, Compound 50)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575687(US11464802, Compound 51)
Affinity DataIC50: <1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585797(US11530229, Compound 12)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585803(US11530229, Compound 18)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585804(US11530229, Compound 19)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585805(US11530229, Compound 20)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585806(US11530229, Compound 21)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585810(US11530229, Compound 25)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585816(US11530229, Compound 31)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585834(US11530229, Compound 49)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585838(US11530229, Compound 53)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585839(US11530229, Compound 54)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585840(US11530229, Compound 55)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585841(US11530229, Compound 56)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585842(US11530229, Compound 57)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585804(US11530229, Compound 19)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585805(US11530229, Compound 20)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585806(US11530229, Compound 21)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585841(US11530229, Compound 56)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585804(US11530229, Compound 19)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585805(US11530229, Compound 20)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585806(US11530229, Compound 21)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585841(US11530229, Compound 56)
Affinity DataIC50: <1nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585789(US11530229, Compound 4)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585796(US11530229, Compound 11)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585801(US11530229, Compound 16)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585802(US11530229, Compound 17)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585808(US11530229, Compound 23)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585796(US11530229, Compound 11)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585825(US11530229, Compound 40)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585829(US11530229, Compound 44)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585833(US11530229, Compound 48)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585773(US11530229, Compound 1)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585789(US11530229, Compound 4)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM585824(US11530229, Compound 39)
Affinity DataIC50:  1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575634(US11464802, Compound 3)
Affinity DataIC50:  3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575635(US11464802, Compound 4)
Affinity DataIC50:  3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Homo sapiens (Human))
Nurix Therapeutics

US Patent
LigandPNGBDBM575642(US11464802, Compound 11)
Affinity DataIC50:  3nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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