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Found 24 with Last Name = 'bennett' and Initial = 'mk'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005795(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)
Affinity DataKi:  67nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368609(CHEMBL604660)
Affinity DataKi:  176nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368611(CHEMBL604864)
Affinity DataKi:  200nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005916(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)
Affinity DataKi:  830nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50230691(CHEMBL3143996)
Affinity DataKi:  2.00E+3nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50230690(CHEMBL3143997)
Affinity DataKi:  2.90E+3nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)
Affinity DataIC50:  5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)
Affinity DataIC50:  8.10nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)
Affinity DataIC50:  14nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277779(CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  21nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277815(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)
Affinity DataIC50:  36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277780(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)
Affinity DataIC50:  41nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277818(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)
Affinity DataIC50:  82nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277778(CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)
Affinity DataIC50:  238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277734(CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  607nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix

Curated by ChEMBL
LigandPNGBDBM50277817(CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)
Affinity DataIC50:  784nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005916(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)
Affinity DataIC50:  900nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005924(2,6-Diamino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrr...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)
Affinity DataIC50:  1.40E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005919(2,6-Diamino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyr...)
Affinity DataIC50:  1.60E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005918(2,6-Diamino-7-furan-2-ylmethyl-3,5-dihydro-pyrrolo...)
Affinity DataIC50:  5.40E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50005921(2,6-Diamino-7-(2-methoxy-benzyl)-3,5-dihydro-pyrro...)
Affinity DataIC50:  3.14E+4nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed