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Found 379 with Last Name = 'bergman' and Initial = 'ye'
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM413866(4-(3-Oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)-2-e...)
Affinity DataIC50:  15nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401715(US10005792, Compound 135 | US10005792, Compound 77)
Affinity DataIC50:  15nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421947(US10494376, Example 55)
Affinity DataIC50:  16nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM422000(US10494376, Example 108)
Affinity DataIC50:  17nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM413867(4-(3-Oxa-8-azabicyclo[3.2.1]octane-8-carbonyl)-N—(...)
Affinity DataIC50:  18nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421943(US10494376, Example 50)
Affinity DataIC50:  19nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM463986(US10787434, Example 4)
Affinity DataIC50:  26nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM50462568(CHEMBL4248047 | US10787434, Example 5)
Affinity DataIC50:  26nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401715(US10005792, Compound 135 | US10005792, Compound 77)
Affinity DataIC50:  29nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM463983(US10787434, Example 1)
Affinity DataIC50:  37nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421942(US10494376, Example 49)
Affinity DataIC50:  38nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421997(US10494376, Example 105)
Affinity DataIC50:  38nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401764(US10005792, Compound 123)
Affinity DataIC50:  40nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421920(US10494376, Example 27)
Affinity DataIC50:  44nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401765(US10005792, Compound 124)
Affinity DataIC50:  48nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401741(US10005792, Compound 103 | US10005792, Compound 13...)
Affinity DataIC50:  50nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401672(US10005792, Compound 35)
Affinity DataIC50:  50nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421973(US10494376, Example 81)
Affinity DataIC50:  51nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421919(US10494376, Example 26)
Affinity DataIC50:  53nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401677(US10005792, Compound 40)
Affinity DataIC50:  57nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421979(US10494376, Example 87)
Affinity DataIC50:  57nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421944(US10494376, Example 51)
Affinity DataIC50:  61nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401713(US10005792, Compound 75)
Affinity DataIC50:  64nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421975(US10494376, Example 83)
Affinity DataIC50:  65nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421995(US10494376, Example 103)
Affinity DataIC50:  65nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421992(US10494376, Example 100)
Affinity DataIC50:  66nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401755(US10005792, Compound 114)
Affinity DataIC50:  66nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421994(US10494376, Example 102)
Affinity DataIC50:  68nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM463985(US10787434, Example 3)
Affinity DataIC50:  70nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM422011(US10494376, Example 124)
Affinity DataIC50:  70nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421914(US10494376, Example 21)
Affinity DataIC50:  70nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM364153(US9856252, 45)
Affinity DataIC50:  83nMAssay Description:The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401673(US10005792, Compound 37)
Affinity DataIC50:  95nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401693(US10005792, Compound 56)
Affinity DataIC50:  98nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM463984(US10787434, Example 2)
Affinity DataIC50:  102nMAssay Description:The 6 μL reactions are run in Greiner brand black 384-well low volume assay plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421954(US10494376, Example 62)
Affinity DataIC50:  102nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421953(US10494376, Example 61)
Affinity DataIC50:  104nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421993(US10494376, Example 101)
Affinity DataIC50:  104nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421930(US10494376, Example 37)
Affinity DataIC50:  105nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421974(US10494376, Example 82)
Affinity DataIC50:  106nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM364124(US9856252, 16)
Affinity DataIC50:  107nMAssay Description:The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401676(US10005792, Compound 39)
Affinity DataIC50:  120nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401741(US10005792, Compound 103 | US10005792, Compound 13...)
Affinity DataIC50:  120nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421962(US10494376, Example 70)
Affinity DataIC50:  121nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM364120(US9856252, 12)
Affinity DataIC50:  122nMAssay Description:The 6 μL assay reactions are run in Greiner brand black 384-well low volume plates. All reactions contained assay buffer (phosphate buffered sal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421983(US10494376, Example 91)
Affinity DataIC50:  123nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421976(US10494376, Example 84)
Affinity DataIC50:  124nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM421991(US10494376, Example 99)
Affinity DataIC50:  127nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401762(US10005792, Compound 121)
Affinity DataIC50:  130nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein arginine N-methyltransferase 5(Homo sapiens (Human))
Ctxt

US Patent
LigandPNGBDBM401774(US10005792, Compound 133)
Affinity DataIC50:  131nMAssay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A histone H4 derived peptide is used as substrate (amino acid ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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