TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universidad De Talca
Curated by ChEMBL
Universidad De Talca
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Competitive inhibition of recombinant GST-tagged VEGFR2 cytoplasmic domain in presence of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Displacement of [3H]neurotensin from NTR1 in human HT29 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Agonist activity at neuropeptide Y Y2 receptor in human SMS-KAN cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 9.70nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant COX2 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Displacement of [125I]PYY from human neuropeptide Y Y2 receptor expressed in HEK293 cells cotransfected with eYFP fusion protein after 2 hrs by compe...More data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universidad De Talca
Curated by ChEMBL
Universidad De Talca
Curated by ChEMBL
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Universit£T Leipzig
Curated by ChEMBL
Universit£T Leipzig
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Displacement of [125I]ghrelin from human eYFP-fused ghrelin receptor expressed in COS7 cells after 75 mins by competitive receptor binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Displacement of [3H]neurotensin from NTR1 in human HT29 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant COX2 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of ovine COX1 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Displacement of [3H]neurotensin from NTR1 in human HT29 cells after 30 mins by liquid scintillation spectrometryMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universidad De Talca
Curated by ChEMBL
Universidad De Talca
Curated by ChEMBL
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of FLK1More data for this Ligand-Target Pair
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Helmholtz-Zentrum Dresden-Rossendorf
Curated by ChEMBL
Affinity DataIC50: 1.15E+5nMAssay Description:Inhibition of ovine COX1 by enzymatic fluorescence assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.80E+3nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 540nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.10E+4nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >3.00E+5nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
University Of Copenhagen
Curated by ChEMBL
University Of Copenhagen
Curated by ChEMBL
Affinity DataEC50: 1.40E+4nMAssay Description:Agonist activity at human GABAAalpha1beta2gamma2S receptor expressed in tsA-201cells by FLIPR membrane potential blue assayMore data for this Ligand-Target Pair