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Found 144 with Last Name = 'bertolla' and Initial = 'c'
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50:  31nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50:  180nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50:  1.50E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50:  1.90E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23569((2S)-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan...)
Affinity DataIC50:  2.50E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23566(3-Carboxamide-coumarin deriv., 43 | 6,8-dichloro-N...)
Affinity DataIC50:  4.30E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23548(3-Carboxamide-coumarin deriv., 44 | 8-bromo-6-chlo...)
Affinity DataIC50:  4.40E+3nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23563(3-Carboxylate-coumarin deriv., 3 | CHEMBL13357 | p...)
Affinity DataIC50:  7.00E+3nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23542(3-Carboxamide-coumarin deriv., 27 | 6-methyl-2-oxo...)
Affinity DataIC50:  8.30E+3nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23564(3-Carboxamide-coumarin deriv., 34 | N-(3,5-dimethy...)
Affinity DataIC50:  9.80E+3nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23567(3-Carboxamide-coumarin deriv., 45 | 8-bromo-6-chlo...)
Affinity DataIC50:  1.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23559(3-Carboxamide-coumarin deriv., 29 | 6-methyl-N-(3-...)
Affinity DataIC50:  1.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23541(3-Carboxamide-coumarin deriv., 26 | 6-methyl-N-(na...)
Affinity DataIC50:  1.50E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23544(3-Carboxamide-coumarin deriv., 4 | 6-(chloromethyl...)
Affinity DataIC50:  1.70E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23547(3-Carboxamide-coumarin deriv., 41 | 6,8-dichloro-2...)
Affinity DataIC50:  1.90E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50:  2.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23545(3-Carboxamide-coumarin deriv., 35 | 6-nitro-2-oxo-...)
Affinity DataIC50:  2.20E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50:  2.30E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23546(3-Carboxamide-coumarin deriv., 36 | 6-bromo-2-oxo-...)
Affinity DataIC50:  2.40E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23565(3-Carboxamide-coumarin deriv., 42 | 6,8-dichloro-N...)
Affinity DataIC50:  2.50E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23537(3-Carboxamide-coumarin deriv., 23 | N-(adamantan-1...)
Affinity DataIC50:  2.90E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataIC50:  3.00E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23556(3-Carboxamide-coumarin deriv., 32 | N-(3-chlorophe...)
Affinity DataIC50:  3.10E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23558(3-Carboxamide-coumarin deriv., 28 | 6-methyl-N-(2-...)
Affinity DataIC50:  3.20E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23568(3-Carboxamide-coumarin deriv., 46 | 8-bromo-6-chlo...)
Affinity DataIC50:  3.20E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23536(3-Carboxamide-coumarin deriv., 22 | N-cyclododecyl...)
Affinity DataIC50:  3.30E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23557(3-Carboxamide-coumarin deriv., 33 | N-(4-chlorophe...)
Affinity DataIC50:  3.40E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23543(2-oxo-N-phenyl-2H-chromene-3-carboxamide | 3-Carbo...)
Affinity DataIC50:  4.20E+4nMpH: 7.9 T: 2°CAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23568(3-Carboxamide-coumarin deriv., 46 | 8-bromo-6-chlo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23566(3-Carboxamide-coumarin deriv., 43 | 6,8-dichloro-N...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23568(3-Carboxamide-coumarin deriv., 46 | 8-bromo-6-chlo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23547(3-Carboxamide-coumarin deriv., 41 | 6,8-dichloro-2...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23549(3-Carboxamide-coumarin deriv., 47 | 6-bromo-8-meth...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23563(3-Carboxylate-coumarin deriv., 3 | CHEMBL13357 | p...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23544(3-Carboxamide-coumarin deriv., 4 | 6-(chloromethyl...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23560(3-Carboxamide-coumarin deriv., 30 | 6-methyl-N-(4-...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23559(3-Carboxamide-coumarin deriv., 29 | 6-methyl-N-(3-...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23558(3-Carboxamide-coumarin deriv., 28 | 6-methyl-N-(2-...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23557(3-Carboxamide-coumarin deriv., 33 | N-(4-chlorophe...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23555(3-Carboxamide-coumarin deriv., 31 | N-(2-chlorophe...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23549(3-Carboxamide-coumarin deriv., 47 | 6-bromo-8-meth...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23544(3-Carboxamide-coumarin deriv., 4 | 6-(chloromethyl...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23541(3-Carboxamide-coumarin deriv., 26 | 6-methyl-N-(na...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23538(3-Carboxamide-coumarin deriv., 20 | 6-methyl-2-oxo...)
Affinity DataIC50: >5.00E+4nMAssay Description: After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23567(3-Carboxamide-coumarin deriv., 45 | 8-bromo-6-chlo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23566(3-Carboxamide-coumarin deriv., 43 | 6,8-dichloro-N...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23568(3-Carboxamide-coumarin deriv., 46 | 8-bromo-6-chlo...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
University of Namur

LigandPNGBDBM23566(3-Carboxamide-coumarin deriv., 43 | 6,8-dichloro-N...)
Affinity DataIC50: >5.00E+4nMAssay Description:After substrate hydrolysis reaction, the absorbance at 405 nm was measured in a microplate reader. Percentages of inhibition at each concentration we...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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