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Found 40 with Last Name = 'betz' and Initial = 'a'
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50:  2nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50:  42nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50:  153nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210129(CHEMBL3885334)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210130(CHEMBL3885037)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50:  3.61E+3nMAssay Description:Inhibition of factor 11a (unknown origin) using S-2366 as substrate incubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210076(CHEMBL3884030)
Affinity DataIC50:  8.31E+3nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50:  9.97E+3nMAssay Description:Inhibition of Lys-plasmin (unknown origin) using Tosyl-Gly-Pro-Lys-4-nitranilide as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50:  1.17E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using S-2366 as substrate incubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using S-2366 as substrate incubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50:  2.14E+4nMAssay Description:Inhibition of Lys-plasmin (unknown origin) using Tosyl-Gly-Pro-Lys-4-nitranilide as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50:  4.09E+4nMAssay Description:Inhibition of factor 11a (unknown origin) using S-2366 as substrate incubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210077(CHEMBL3883550)
Affinity DataIC50:  5.32E+4nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of factor 11a (unknown origin) using S-2366 as substrate incubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 12a (unknown origin) using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using N-Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using N-Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 12a (unknown origin) using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of tPA (unknown origin) using Methylsulfonyl-D-Phe-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 12a (unknown origin) using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using N-Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Lys-plasmin (unknown origin) using Tosyl-Gly-Pro-Lys-4-nitranilide as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 12a (unknown origin) using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210073(CHEMBL3883461)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of tPA (unknown origin) using Methylsulfonyl-D-Phe-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210074(CHEMBL3883423)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of tPA (unknown origin) using Methylsulfonyl-D-Phe-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of factor 10a (unknown origin) using N-Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210127(CHEMBL3884851)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Lys-plasmin (unknown origin) using Tosyl-Gly-Pro-Lys-4-nitranilide as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210075(CHEMBL3883788)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of tPA (unknown origin) using Methylsulfonyl-D-Phe-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of alpha-thrombin (unknown origin) using D-Phe-Pip-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of tPA (unknown origin) using Methylsulfonyl-D-Phe-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of factor 12a (unknown origin) using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of Lys-plasmin (unknown origin) using Tosyl-Gly-Pro-Lys-4-nitranilide as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210072(CHEMBL3884830)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of factor 10a (unknown origin) using N-Z-D-Arg-Gly-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Global Blood Therapeutics

Curated by ChEMBL
LigandPNGBDBM50210128(CHEMBL3884218)
Affinity DataIC50: >3.00E+6nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA as substrate preincubated for 30 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed