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Found 154 with Last Name = 'bilimoria' and Initial = 'd'
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139666(5-(4-Acetyl-phenyl)-3-(2,4-dimethyl-benzenesulfony...)
Affinity DataIC50:  390nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126676(2-[4-(4'-Chloro-4-methoxy-biphenyl-2-ylmethoxy)-ph...)
Affinity DataIC50:  620nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126679((S)-2-(2,4-dichloro-N-(3-nitrobenzyl)benzamido)-3-...)
Affinity DataIC50:  700nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139669(3-(4-Chloro-2-methyl-benzenesulfonylamino)-5-pheny...)
Affinity DataIC50:  750nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126666(2-[(3-Cyano-benzyl)-(2,4-dichloro-benzoyl)-amino]-...)
Affinity DataIC50:  800nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139657(3-(2,4-Dimethyl-benzenesulfonylamino)-5-phenyl-thi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139657(3-(2,4-Dimethyl-benzenesulfonylamino)-5-phenyl-thi...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139683(3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYL...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139682(3-[(4-Chloro-benzoyl)-methyl-amino]-5-phenyl-thiop...)
Affinity DataIC50:  1.20E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126663((S)-2-(2,4-dichloro-N-(3-chlorobenzyl)benzamido)-3...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139676(3-[(2,4-Dimethyl-benzoyl)-methyl-amino]-5-phenyl-t...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139659(5-(4-Acetyl-phenyl)-3-(toluene-2-sulfonylamino)-th...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126661((2S)-2-[(2,4-DICHLORO-BENZOYL)-(3-TRIFLUOROMETHYL-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139673(2-[(2,4-Dichloro-benzoyl)-(3-trifluoromethyl-benzy...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126668((S)-2-(2,4-dichloro-N-(3-methylbenzyl)benzamido)-3...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139658(5-(4-Methanesulfonyl-phenyl)-3-(toluene-2-sulfonyl...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139681(3-[Ethyl-(4-methyl-benzoyl)-amino]-5-phenyl-thioph...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139675(3-[Methyl-(4-methyl-benzoyl)-amino]-5-phenyl-thiop...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126675(2-[(2,4-Dichloro-benzoyl)-(1-oxy-pyridin-3-ylmethy...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132832((S)-2-[(3-Bromo-benzyl)-(4-chloro-2-iodo-benzoyl)-...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139688(3-[isopropyl(4-methylbenzoyl)amino]-5-phenylthioph...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126671(2-[(5-Bromo-thiophen-2-ylmethyl)-(2,4-dichloro-ben...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126673((S)-2-(2,4-dichloro-N-(3-fluorobenzyl)benzamido)-3...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126667((S)-2-(N-(3-bromobenzyl)-2,4-dichlorobenzamido)-3-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126667((S)-2-(N-(3-bromobenzyl)-2,4-dichlorobenzamido)-3-...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132822((S)-2-[(3-Bromo-benzyl)-(4-chloro-2-methyl-benzoyl...)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50153760(5-(4-Fluoro-phenyl)-3-(pyridine-2-sulfonylamino)-t...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration for NS5B RNA-dependent RNA polymerase of Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50153761(5-Pyridin-4-yl-3-(toluene-2-sulfonylamino)-thiophe...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibitory concentration for NS5B RNA-dependent RNA polymerase of Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139656(3-(4-Chloro-benzenesulfonylamino)-5-phenyl-thiophe...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139672(5-Phenyl-3-(toluene-4-sulfonylamino)-thiophene-2-c...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139684(3-[(2,4-Dimethyl-benzenesulfonyl)-methyl-amino]-5-...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132829((S)-2-[(3-Bromo-benzyl)-(2-bromo-4-chloro-benzoyl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139663(3-(4-Chloro-2,5-dimethyl-benzenesulfonylamino)-5-p...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration for NS5B RNA-dependent RNA polymerase of Hepatitis C virusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139661(5-Phenyl-3-(toluene-2-sulfonylamino)-thiophene-2-c...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139663(3-(4-Chloro-2,5-dimethyl-benzenesulfonylamino)-5-p...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132831((S)-2-[(3-Bromo-benzyl)-(4-chloro-2-ethyl-benzoyl)...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126677((S)-2-(2,4-dichloro-N-(4-(thiazol-2-yl)benzyl)benz...)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132821((S)-2-[(3-Bromo-benzyl)-(2,4-dimethyl-benzoyl)-ami...)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126680((S)-2-(2,4-dichloro-N-(2-cyanobenzyl)benzamido)-3-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139662(5-Phenyl-3-(toluene-3-sulfonylamino)-thiophene-2-c...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126674((S)-2-(2,4-dichloro-N-(4-cyanobenzyl)benzamido)-3-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126670(2-[(2-Bromo-benzyl)-(2,4-dichloro-benzoyl)-amino]-...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126678(2-[Benzyl-(2,4-dichloro-benzoyl)-amino]-3-phenyl-p...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126669((2S)-2-[(5-BENZOFURAN-2-YL-THIOPHEN-2-YLMETHYL)-(2...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126659(2-[(3-Bromo-benzyl)-(2,4-dichloro-benzoyl)-amino]-...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50139686(3-(Cyclohexanecarbonyl-isopropyl-amino)-5-phenyl-t...)
Affinity DataIC50:  9.00E+3nMAssay Description:In vitro inhibition of Hepatitis C polymerase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126665(2-[(4-Bromo-benzyl)-(2,4-dichloro-benzoyl)-amino]-...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126672((S)-2-[(3-Bromo-benzyl)-(4-chloro-benzoyl)-amino]-...)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein(Hepatitis C virus (HCV))
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50132823((S)-2-[(3-Bromo-benzyl)-(2,4-dimethoxy-benzoyl)-am...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B activity.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Shire Biochem

Curated by ChEMBL
LigandPNGBDBM50126660((S)-2-(2,4-dichloro-N-(pyridin-3-ylmethyl)benzamid...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibitory activity against Hepatitis C RNA dependent RNA polymerase Nonstructural protein 5B (NS5B polymerase) expressed from baculovirus-infected S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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