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Found 367 with Last Name = 'billheimer' and Initial = 'j'
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450347(CHEMBL431940)
Affinity DataIC50:  3nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037666(3-(2,4-Difluoro-phenyl)-1-[8-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037663(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037622(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037664(3-Cyclohexyl-1-[5-(4,5-diphenyl-1H-imidazol-2-ylsu...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450346(CHEMBL300883)
Affinity DataIC50:  10nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037638(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  10nMAssay Description:In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomes by using AIV assay.More data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033960(CHEMBL11612 | N-{5-[4,5-Bis-(4-methoxy-phenyl)-1H-...)
Affinity DataIC50:  11nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037634(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037625(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Mus musculus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50285443(Benzooxazol-2-yl-[5-(4,5-diphenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of Acyl coenzyme A:cholesterol acyltransferase in J774 Macrophage cell cultureMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037665(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037637(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037636(CHEMBL119759 | [5-(4,5-Diphenyl-1H-imidazol-2-ylsu...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033949(1-[5-(4,5-Dicyclohexyl-1H-imidazol-2-ylsulfanyl)-p...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033950(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diisopropyl-1H-i...)
Affinity DataIC50:  20nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037642(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  23nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037650(2-(2,4-Difluoro-phenyl)-N-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450352(CHEMBL406757)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037653(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037661(2-Cyclohexyl-N-[5-(4,5-diphenyl-1H-imidazol-2-ylsu...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037620(3-(2,4-Difluoro-phenyl)-1-[3-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037656(CHEMBL115686 | N-[5-(4,5-Diphenyl-1H-imidazol-2-yl...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037624(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033966(CHEMBL11267 | N-[5-[(1H,9H-dibenzo[4,5:8,9] [1,3]d...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50285426(2-[5-(4,5-diphenyl-1H-2-imidazolylsulfanyl)pentyls...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037648(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033971(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  30nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50450357(CHEMBL48164)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase (ACAT) in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037623(CHEMBL119271 | [5-(4,5-Diphenyl-1H-imidazol-2-ylsu...)
Affinity DataIC50:  34nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037654(1-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50285434(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50285442(Benzooxazol-2-yl-{5-[4,5-bis-(4-methoxy-phenyl)-1H...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomes was measured by using AIV assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033975(1-{5-[4,5-Bis-(3-methoxy-phenyl)-1H-imidazol-2-yls...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033998(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033997(1-{5-[4,5-Bis-(4-fluoro-phenyl)-1H-imidazol-2-ylsu...)
Affinity DataIC50:  40nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037615(1-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037628(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033952(1-{5-[4,5-Bis-(4-dimethylamino-phenyl)-1H-imidazol...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037633(CHEMBL333653 | [5-(4,5-Diphenyl-1H-imidazol-2-ylsu...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033955(CHEMBL11201 | N-{5-[4,5-Bis-(4-dimethylamino-pheny...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50033957(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  50nMAssay Description:Concentration required to inhibit 50% activity of Acyl coenzyme A:cholesterol acyltransferase 1 in vitro using rat liver microsome.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037644(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase in rat hepatic microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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