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Found 35 with Last Name = 'bills' and Initial = 'gf'
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)
Affinity DataKi:  4.5nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferase with respect to FPPMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287707((E)-3-Carboxy-2-(16-hydroxy-hexadecyl)-pent-2-ened...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM24226(1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxypheny...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM50287708((E)-3-Methoxycarbonyl-2-(16-sulfooxy-hexadecyl)-pe...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50287709((E)-3-Carboxy-2-(16-sulfooxy-hexadecyl)-pent-2-ene...)
Affinity DataIC50:  14nMAssay Description:In vitro inhibition of human recombinant Protein farnesyltransferaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242053(6,8-didec-(1Z)-enyl-5,7-dimethyl-2,3-dihydro-1H-in...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124971((2R,3S)-5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetra...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124964(6,8'-Dihydroxy-5,8,5',6'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124966((8R,9R)-2,4,5-Trihydroxy-8,9-dimethyl-1-((2S,3R)-5...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124967(5,6,8,5',6',8'-Hexahydroxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242056(CHEMBL469856 | fuscinarin)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of MIP1alpha binding to human CCR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389213(CHEMBL2063169)
Affinity DataIC50: >2.27E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389212(CHEMBL2063168)
Affinity DataIC50: >2.34E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Fundacion Medina

Curated by ChEMBL
LigandPNGBDBM50389211(CHEMBL2063167)
Affinity DataIC50: >2.40E+4nMAssay Description:Inhibition of human ERG expressed in HEK293 cells coexpressing Kir2.3 after 30 mins by FluxOR based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50373178(PYCNIDIONE)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of stromelysin mediated beta-casein cleavageMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242054(CHEMBL469855 | ophiobolin C)
Affinity DataIC50:  4.00E+4nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124970(6-Hydroxy-5,8,5',6',8'-pentamethoxy-2,3,2',3'-tetr...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50478520(BARCELONEIC ACID A)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human recombinant FPTase by Ras farnesyl-protein-transferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478406(Integrasone)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124968(Acetic acid 6,8,5',6',8'-pentaacetoxy-2,3,2',3'-te...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124969(5,6,8,5',6',8'-Hexamethoxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50242055(19,20-epoxycytochalasin Q | CHEMBL449278)
Affinity DataIC50:  6.00E+4nMAssay Description:Displacement of [125I]gp-120 from human CCR5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124965(5,6-Dihydroxy-8,5',6',8'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124965(5,6-Dihydroxy-8,5',6',8'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124968(Acetic acid 6,8,5',6',8'-pentaacetoxy-2,3,2',3'-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124965(5,6-Dihydroxy-8,5',6',8'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124965(5,6-Dihydroxy-8,5',6',8'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124969(5,6,8,5',6',8'-Hexamethoxy-2,3,2',3'-tetramethyl-2...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in coupled transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124970(6-Hydroxy-5,8,5',6',8'-pentamethoxy-2,3,2',3'-tetr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50124964(6,8'-Dihydroxy-5,8,5',6'-tetramethoxy-2,3,2',3'-te...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HIV-1 integrase in strand transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed