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Found 112 with Last Name = 'bischoff' and Initial = 'h'
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(CHEMBL479527 | torcetrapib)
Affinity DataIC50:  3nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(CHEMBL479527 | torcetrapib)
Affinity DataIC50:  18nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312718(CHEMBL479527 | torcetrapib)
Affinity DataIC50:  20nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312720((S)-3'-((S)-fluoro(4-(trifluoromethyl)phenyl)methy...)
Affinity DataIC50:  24nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50:  30nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312719((S)-2-cyclopentyl-3-((S)-fluoro(4-(trifluoromethyl...)
Affinity DataIC50:  31nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312730((S)-(4'-cyclohexyl-5'-hydroxy-2'-isopropyl-6',8'-d...)
Affinity DataIC50:  33nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312717((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...)
Affinity DataIC50:  39nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312714((S)-4-cyclohexyl-2-cyclopentyl-3-((S)-fluoro(4-(tr...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312732((S)-(4'-cyclohexyl-2'-cyclopentyl-5'-hydroxy-6',8'...)
Affinity DataIC50:  55nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344969(CHEMBL1778340 | [(4R,6S)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  56nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312731((S)-(4-cyclohexyl-2-cyclopentyl-5-hydroxy-7,7-dime...)
Affinity DataIC50:  60nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312716((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-fluoro(4-...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human plasma CETP assessed as [3H]cholesterol ester transfer after 18 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312728((S)-(2',4'-dicyclopentyl-5'-hydroxy-6',8'-dihydro-...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312711((S)-4'-cyclohexyl-3'-((S)-hydroxy(4-(trifluorometh...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312715((S)-4'-cyclohexyl-3'-((S)-fluoro(4-(trifluoromethy...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312729((S)-(4-cyclohexyl-5-hydroxy-2-isopropyl-7,7-dimeth...)
Affinity DataIC50:  70nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312713((S)-4-cyclohexyl-3-((S)-fluoro(4-(trifluoromethyl)...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312709(CHEMBL1080749 | trans-4-cyclohexyl-3-(hydroxy(4-(t...)
Affinity DataIC50:  80nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312727((S)-(2,4-dicyclopentyl-5-hydroxy-7,7-dimethyl-5,6,...)
Affinity DataIC50:  90nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312712((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-hydroxy(4...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312710(CHEMBL1080750 | trans-4-cyclohexyl-2-cyclopentyl-3...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344972(1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1-...)
Affinity DataIC50:  112nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344971((1-{2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1...)
Affinity DataIC50:  131nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344970(2-[(4R,6S)-8-Chloro-6-(2,3-dimethoxy-phenyl)-1-iso...)
Affinity DataIC50:  162nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50118897((1-{2-[1-(3-Acetoxy-2,2-dimethyl-propyl)-7-chloro-...)
Affinity DataIC50:  213nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339917(1-(2-((1R,5R)-7-chloro-5-(2,3-dimethoxyphenyl)-1-i...)
Affinity DataIC50:  220nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344973(2-((3R,5S)-7-chloro-5-(2,3-dimethoxyphenyl)-1-(3-h...)
Affinity DataIC50:  223nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50118898((1-{2-[7-Chloro-5-(2,3-dimethoxy-phenyl)-1-(3-hydr...)
Affinity DataIC50:  260nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312717((S)-4-cyclohexyl-2-cyclopentyl-7,7-dimethyl-3-(4-(...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human plasma CETP assessed as cholesterol ester transfer after 24 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312725((S)-(2'-cyclopentyl-5'-hydroxy-4'-isopropyl-6',8'-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339916(CHEMBL1761660 | trans-rac-7-chloro-1-isobutyl-5-(2...)
Affinity DataIC50:  370nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339918(CHEMBL1761662 | trans-rac-1-(2-(7-chloro-5-(2,3-di...)
Affinity DataIC50:  450nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312705((S)-benzyl 4-(2-cyclopentyl-5-hydroxy-7,7-dimethyl...)
Affinity DataIC50:  500nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339919(CHEMBL1761661 | trans-rac-1-(2-(7-chloro-1-isobuty...)
Affinity DataIC50:  500nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312724((S)-(2-cyclopentyl-5-hydroxy-4-isopropyl-7,7-dimet...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312722((S)-(2'-cyclopentyl-5'-hydroxy-4'-propyl-6',8'-dih...)
Affinity DataIC50:  600nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339920(CHEMBL1761659 | trans-rac-1-(2-(7-chloro-5-(2-chlo...)
Affinity DataIC50:  930nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339921(CHEMBL1761656 | trans-rac-2-(7-chloro-5-(2,3-dimet...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339922(CHEMBL1761658 | trans-rac-2-(1-(2-(7-chloro-5-(2-c...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50344968(CHEMBL1777819 | [(4S,6R)-8-Chloro-6-(2,3-dimethoxy...)
Affinity DataIC50:  1.42E+3nMAssay Description:Inhibition of recombinant squalene synthase assessed as conversion of trans,trans-[1-3H]farnesyl pyrophosphate to [3H]squalene after 10 mins by liqui...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene synthase(Homo sapiens (Human))
Bayer Pharma

Curated by ChEMBL
LigandPNGBDBM50339923(CHEMBL1761655 | trans-rac-2-(5-(2-methoxyphenyl)-7...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of squalene synthase assessed as conversion of [3H]farnesyl phosphate to [3H]squalene after 10 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Bayer Healthcare

Curated by ChEMBL
LigandPNGBDBM50312733(((5S)-4-sec-butyl-2-cyclopentyl-5-hydroxy-7,7-dime...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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