Compile Data Set for Download or QSAR
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Found 13 with Last Name = 'bishop' and Initial = 'ac'
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Affinity DataKi:  230nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Affinity DataKi:  710nMAssay Description:Inhibition of TCPTP I220A mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118762(2-(Oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thioph...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118792(2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]P...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of PTP1B V49A mutantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50118762(2-(Oxalyl-amino)-4,5,6,7-tetrahydro-benzo[b]thioph...)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50187184(2-(carboxyformamido)-5,5,7,7-tetramethyl-4,5,6,7-t...)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272021(CHEMBL4128743)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant using pNPP as substrate incubated for 90 mins by q...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272021(CHEMBL4128743)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli crude cell lysat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272020(CHEBI:52107 | CHEMBL454668)
Affinity DataIC50:  125nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain using pNPP as substrate incubated for 90 mins by quen...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College

Curated by ChEMBL
LigandPNGBDBM50272020(CHEBI:52107 | CHEMBL454668)
Affinity DataIC50:  250nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain overexpressed in Escherichia coli crude cell lysate u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed