TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 710nMAssay Description:Inhibition of TCPTP I220A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of TCPTPMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 1.00E+4nMAssay Description:Inhibition of PTP1B I219A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 2.70E+4nMAssay Description:Inhibition of PTP1B V49A mutantMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: 3.40E+4nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of wild type PTP1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant using pNPP as substrate incubated for 90 mins by q...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of allosterically sensitized His6-tagged human PTP1B catalytic domain P87C/A122C mutant overexpressed in Escherichia coli crude cell lysat...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain using pNPP as substrate incubated for 90 mins by quen...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 7(Homo sapiens (Human))
Amherst College
Curated by ChEMBL
Amherst College
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of allosterically sensitized mutant form of His6-tagged human HePTP catalytic domain overexpressed in Escherichia coli crude cell lysate u...More data for this Ligand-Target Pair