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Found 104 with Last Name = 'black-schaefer' and Initial = 'cl'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201303(1-(4-(4-amino-7-(pyrimidin-5-yl)thieno[3,2-c]pyrid...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201330(1-(4-(4-amino-7-(pyridin-4-yl)thieno[3,2-c]pyridin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201323(1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201330(1-(4-(4-amino-7-(pyridin-4-yl)thieno[3,2-c]pyridin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201303(1-(4-(4-amino-7-(pyrimidin-5-yl)thieno[3,2-c]pyrid...)
Affinity DataIC50:  8nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201307(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...)
Affinity DataIC50:  9nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201323(1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...)
Affinity DataIC50:  9nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201314(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  10nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201319(1-(4-(4-amino-7-(3-(methylcarbamoyl)phenyl)thieno[...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201327(1-(4-(4-amino-7-(4-hydroxyphenyl)thieno[3,2-c]pyri...)
Affinity DataIC50:  11nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  13nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201318(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  15nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201308(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201320(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  16nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201308(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  21nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201311(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  22nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137758(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  22nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137758(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  22nMAssay Description:Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201328(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-1-m...)
Affinity DataIC50:  23nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201310(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  25nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201322(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...)
Affinity DataIC50:  26nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201325(1-(4-(4-amino-2-methylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  27nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201327(1-(4-(4-amino-7-(4-hydroxyphenyl)thieno[3,2-c]pyri...)
Affinity DataIC50:  29nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201309(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  30nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201310(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201307(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201302(1-(4-(4-amino-7-phenylthieno[3,2-c]pyridin-3-yl)ph...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201301(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  38nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201314(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201305(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  45nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201320(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201309(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  48nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137762(2-Chloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6,7-t...)
Affinity DataIC50:  54nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201311(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201319(1-(4-(4-amino-7-(3-(methylcarbamoyl)phenyl)thieno[...)
Affinity DataIC50:  56nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201317(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...)
Affinity DataIC50:  56nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201301(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137786(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  67nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137786(2,4-Dichloro-N-[3-cyano-6-(4-hydroxy-phenyl)-4,5,6...)
Affinity DataIC50:  70nMAssay Description:Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137768(2,4-Dichloro-N-(3-cyano-6-phenyl-4,5,6,7-tetrahydr...)
Affinity DataIC50:  70nMAssay Description:Antibacterial activity against UDP-MurNAc-pentapeptide synthetase from Streptococcus pneumoniae.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201317(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...)
Affinity DataIC50:  72nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201304(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  75nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201315(2-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-N-m...)
Affinity DataIC50:  94nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201322(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-p...)
Affinity DataIC50:  141nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201318(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  147nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201331(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-o...)
Affinity DataIC50:  152nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201305(1-(4-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-(...)
Affinity DataIC50:  198nMAssay Description:Inhibition of human KDR phosphorylation in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201324(1-(3-(4-aminothieno[3,2-c]pyridin-3-yl)phenyl)-3-m...)
Affinity DataIC50:  250nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50201323(1-(4-(4-amino-7-(pyridin-3-yl)thieno[3,2-c]pyridin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase(Streptococcus pneumoniae (Firmicutes))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50137760(2,4-dichloro-N-(3-cyano-5,6-dihydro-4H-cyclopenta[...)
Affinity DataIC50:  300nMAssay Description:Inhibition of D-Ala-D-Ala adding enzyme (MurF) from Streptococcus pneumoniase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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