Affinity DataKi: 120nM ΔG°: -39.1kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 220nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
Affinity DataKi: 250nM ΔG°: -37.3kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 590nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 670nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 870nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nM ΔG°: -33.5kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 1.40E+3nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibitory constant of the compound against Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Inhibitory constant of the compound against Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nM ΔG°: -31.4kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+3nM ΔG°: -30.9kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nM ΔG°: -30.0kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 5.00E+3nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 6.50E+3nMAssay Description:Percent inhibition of compound against Protein-tyrosine phosphatase 1B at a 65 microM concentrationMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nM ΔG°: -27.8kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Pharmacia
Curated by ChEMBL
Pharmacia
Curated by ChEMBL
Affinity DataKi: 1.40E+4nMAssay Description:Inhibitory activity against human protein tyrosine phosphatase 1B (PTP1B)More data for this Ligand-Target Pair
Affinity DataKi: 3.00E+4nM ΔG°: -25.6kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-22.6kJ/molepH: 7.2 T: 2°CAssay Description:Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50%...More data for this Ligand-Target Pair