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Found 503 with Last Name = 'bobok' and Initial = 'a'
LigandPNGBDBM50610205(CHEMBL5268764)
Affinity DataKi:  0.300nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50610205(CHEMBL5268764)
Affinity DataKi:  0.400nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  0.400nMAssay Description:Negative allosteric modulation of alpha1 GABAA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605870(CHEMBL5196475)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50144861(3-(5-Methyl-isoxazol-3-yl)-6-(pyridin-2-ylmethoxy)...)
Affinity DataKi:  0.5nMAssay Description:Negative allosteric modulation of alpha5 GABAA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066519(CHEMBL3403102)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066730(CHEMBL3403126)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50610197(CHEMBL5283158)
Affinity DataKi:  1.70nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066735(CHEMBL3403121)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605882(CHEMBL5202280)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066731(CHEMBL3403125)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50610218(CHEMBL5279431)
Affinity DataKi:  2nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066366(CHEMBL3401592)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066520(CHEMBL3403101)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066734(CHEMBL3403122)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.

Curated by ChEMBL
LigandPNGBDBM50001922(2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; ...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066728(CHEMBL3403128)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066521(CHEMBL3403100)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066671(CHEMBL3403146)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066729(CHEMBL3403127)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605891(CHEMBL5174560)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066732(CHEMBL3403124)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605874(CHEMBL5207799)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066713(CHEMBL3403145)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066751(CHEMBL3403094)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605904(CHEMBL5179688)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066362(CHEMBL3401594)
Affinity DataKi:  3.30nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50323373(1,2-dicyclohexyl-3-(pyridin-3-yl)propan-1-one O-3-...)
Affinity DataKi:  3.40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066754(CHEMBL3403091)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50610197(CHEMBL5283158)
Affinity DataKi:  3.60nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605888(CHEMBL5179759)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066498(CHEMBL3401580)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605869(CHEMBL5185502)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605868(CHEMBL5186978)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066736(CHEMBL3403120)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM133427(US8846719, 112)
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
LigandPNGBDBM133427(US8846719, 112)
Affinity DataKi:  4.40nMAssay Description:Negative allosteric modulation of alpha5 GABAA (unknown origin)More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066753(CHEMBL3403092)
Affinity DataKi:  4.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605894(CHEMBL5176630)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50605890(CHEMBL5200451)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50066752(CHEMBL3403093)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]R21412 from recombinant human mGluR5a expressed in human A18 cell membrane homogenateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236748(CHEMBL4081358)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139454(CHEMBL3764419)
Affinity DataKi:  5.20nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]R21412 from from in Sprague-Dawley rat cerebrocortical membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50139455(CHEMBL3765114)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50610203(CHEMBL5267248)
Affinity DataKi:  5.40nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50236745(CHEMBL4097994)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM86716(CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...)
Affinity DataKi:  6.70nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM86716(CAS_63540-28-3 | CHEMBL239800 | Fenobam | NSC_2162...)
Affinity DataKi:  6.76nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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