Affinity DataKi: 0.300nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.400nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 0.400nMAssay Description:Negative allosteric modulation of alpha1 GABAA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Negative allosteric modulation of alpha5 GABAA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.70nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 1.90nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of flumazenil from alpha5 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 2nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.
Curated by ChEMBL
Gedeon Richter Plc., Gy�Mroi�T 19-21, Budapest H-1103, Hungary.
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Displacement of [3H]-UK14304 from recombinant human alpha2c adrenergic receptor expressed in CHOK1 cell membranes after 30 mins by scintillation coun...More data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-M-MPEP from rat mGLUR5More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nMAssay Description:Negative allosteric modulation of alpha5 GABAA (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]Ro151788 from human recombinant alpha5beta3gamma2 GABAA receptor stably expressed in HEK293 cell membrane assessed as inhibition ...More data for this Ligand-Target Pair
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]-M-MPEP from rat cerebrocortical mGluR5 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.90nMAssay Description:Displacement of [3H]R21412 from recombinant human mGluR5a expressed in human A18 cell membrane homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]R21412 from from in Sprague-Dawley rat cerebrocortical membranesMore data for this Ligand-Target Pair
Affinity DataKi: 5.30nMAssay Description:Displacement of [3H]MPEP from rat mGlu5 receptor expressed in rat cerebrocortical membrane measured after 1 hrMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nMAssay Description:Displacement of flumazenil from alpha1 GABAA receptor (unknown origin)More data for this Ligand-Target Pair
Ligand Info
Affinity DataKi: 6.5nMAssay Description:Displacement of [3H]M-MPEP from mGluR5 in Sprague-Dawley rat cerebrocortical membranes after 60 minsMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Antagonist activity at human mGLUR1More data for this Ligand-Target Pair
Affinity DataKi: 6.76nMAssay Description:Binding affinity to human mGluR5More data for this Ligand-Target Pair