Compile Data Set for Download or QSAR
maximum 50k data
Found 20 with Last Name = 'bohn' and Initial = 'k'
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183409(CHEMBL3822531)
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using increasing AFC substr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183409(CHEMBL3822531)
Affinity DataKi:  2.90E+3nMAssay Description:Non-competitive inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes with increasing [14C]-S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50384449(CHEMBL2035530)
Affinity DataIC50:  400nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183409(CHEMBL3822531)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183444(CHEMBL3823651)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human ABCG2 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183445(CHEMBL3822621)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of human MDR1 expressed in Sf9 cell membranes assessed as reduction in [125I]-IAAP binding incubated for 20 mins under UV light irradiatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260355(CHEMBL2063071)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/FLV1000 cells assessed as increase in calcein-AM accumulation incubated for 10 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260356(CHEMBL2063072)
Affinity DataIC50:  1.33E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/FLV1000 cells assessed as increase in calcein-AM accumulation incubated for 10 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183447(CHEMBL3823076)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183446(CHEMBL3822563)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50260357(CHEMBL2063070)
Affinity DataIC50:  2.82E+4nMAssay Description:Inhibition of ABCG2 in human MCF7/FLV1000 cells assessed as increase in calcein-AM accumulation incubated for 10 mins by flow cytometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183442(CHEMBL3823998)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183441(CHEMBL3823782)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183440(CHEMBL3823382)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183412(CHEMBL3822723)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183411(CHEMBL3824039)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183410(CHEMBL3823389)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-S-isoprenylcysteine O-methyltransferase(Homo sapiens (Human))
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50183443(CHEMBL3823479)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human isoprenylcysteine carboxyl methyltransferase expressed in yeast His10myc3N-Icmt membranes using AFC substrate and [14C]-SAM and i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed