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Found 23 with Last Name = 'bolger' and Initial = 'g'
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataIC50:  680nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072317(CHEMBL3408841)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072319(CHEMBL3408622)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072318(CHEMBL3408617)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50326056((1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazin...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 2(Rattus norvegicus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of rat hapatic, acyl coA cholesterol acetyltransferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072320(CHEMBL3408847)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of serotonin 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072317(CHEMBL3408841)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of serotonin 5-HT2A receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072317(CHEMBL3408841)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50072317(CHEMBL3408841)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of cathepsin G (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM12311((1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxop...)
Affinity DataIC50:  6.20E+3nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein phosphatase 2B catalytic subunit beta isoform(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human PP2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of alpha2A adrenergic receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of 5-LO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of cathepsin G (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of dopamine D1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50398052(CHEMBL2181776)
Affinity DataIC50: <1.00E+4nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM12311((1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxop...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human CatB after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human leukocyte elastase after 60 mins fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Mus musculus)
Boehringer Ingelheim (Canada)

Curated by ChEMBL
LigandPNGBDBM50336545((1R,2S)-1-((2S,4R)-4-(8-bromo-2-(2-isobutyramidoth...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of mouse recombinant cathepsin E by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed