TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataKi: 68nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataKi: 470nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 126nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Binding affinity to ABL (unknown origin)More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 444nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 457nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Binding affinity to LCK (unknown origin)More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 930nMAssay Description:Inhibition of FTO (unknown origin) demethylation activity by HPLC assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human N-terminal His-tagged SIRT2 expressed in Escherichia coli using p53 (Gln-Pro-Lys-Lys(Ac)) (317 to 320 residues) as substrate incu...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to FGFR1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to Aurora A (unknown origin)More data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to TRAK-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to PKC beta2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to CLK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Binding affinity to ECK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to Aurora A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to MAP3K9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to ABL (unknown origin)More data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to TRAK-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Binding affinity to MAP3K9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Binding affinity to MST2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.00E+3nMAssay Description:Binding affinity to MAP3K9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
Affinity DataIC50: 8.98E+3nMAssay Description:Inhibition of ALKBH5 (unknown origin) demethylation activityMore data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity to TRAK-A (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Binding affinity to CLK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+4nMAssay Description:Binding affinity to VEGFR2 (unknown origin)More data for this Ligand-Target Pair
TargetTumor necrosis factor receptor superfamily member 1A(Homo sapiens (Human))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Binding affinity to TRAK-A (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Kyoto Prefectural University Of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.48E+4nMAssay Description:Inhibition of LSD1 (unknown origin) using H3K4me2 peptide as substrate preincubated for 15 mins followed by substrate addition and measured after 30 ...More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to ABL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to ABL (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to LCK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity to LCK (unknown origin)More data for this Ligand-Target Pair