Affinity DataKi: 0.160nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 2.60nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 26nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 37nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 100nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 170nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 220nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 330nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 370nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 420nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 450nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2C adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 530nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 550nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 570nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 660nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 780nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 780nMAssay Description:Ability to displace [3H]prazosin from cloned human Alpha-1D adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 780nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2B adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 800nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 900nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Ability to displace [3H]rauwolscine from cloned human Alpha-2A adrenergic receptorMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Compound was tested for its ability to inhibit uptake of [3H]- GABA by cloned human GAT-1 transporterMore data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 2(Rattus norvegicus)
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against rat GABA transporter-2 (rGAT2)More data for this Ligand-Target Pair
TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Synaptic Pharmaceutical
Curated by ChEMBL
Synaptic Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory activity against human GABA transporter-1 (hGAT1)More data for this Ligand-Target Pair