Affinity DataKi: 0.100nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.100nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 0.190nMAssay Description:Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 0.240nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Displacement of [125I]-secretin-27 from secretin receptor expressed in CHO cells by gamma-spectrometer analysisMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.10nMAssay Description:Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I]-secretin-27 from secretin receptor expressed in CHO cells by gamma-spectrometer analysisMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 11nMAssay Description:Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: 54nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 90nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rattus norvegicus (rat))
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 160nMAssay Description:Binding affinity to Alpha-1 adrenergic receptor by displacement of [3H]prazosinMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 650nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 690nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
TargetAlpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor(RAT)
Pfizer
Curated by ChEMBL
Pfizer
Curated by ChEMBL
Affinity DataKi: 4.83E+3nMAssay Description:Binding affinity to alpha-2 adrenergic receptor by displacement of [3H]clonidineMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human ER betaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human ER betaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human ER betaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DHT from human Androgen receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Estrogen receptor alphaMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of radioligand from human Progesterone receptorMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of 10 nM [3H]dexamethasone from human Glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human PRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.520nMAssay Description:Compound was tested in vitro for its Tachykinin receptor 1 affinity by the displacement of [125I]-Bolton-Hunter substance p from human IM-9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Transrepression activity at glucocorticoid receptor in human SW1353 cells assessed as repression of IL-1-induced MMP-13 production after 24 hrs by EL...More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.770nMAssay Description:Binding affinity towards Tachykinin receptor 1 in human IM-9 cells using [3H]-substance P as ligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Binding affinity to human GRMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Compound was evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4DMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:In vitro affinity to the cholecystokinin type B receptor in guinea pig cortex assayed using [125I]-BH-CCK-8 as radioligandMore data for this Ligand-Target Pair