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Found 40 with Last Name = 'bosc' and Initial = 'e'
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073221(CHEMBL3408420)
Affinity DataKi:  2.70E+4nMAssay Description:Competitive inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073222(CHEMBL3125572)
Affinity DataKi:  5.06E+4nMAssay Description:Competitive inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  50nMAssay Description:Compound was tested in vitro for its ability to inhibit human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285111((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  130nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285107((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  490nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285106((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  540nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285112((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-trifluorome...)
Affinity DataIC50:  680nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285109((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-trifluorome...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285107((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285111((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285106((2S,5R,6S)-6-Methanesulfonyloxy-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeutrophil elastase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.40E+4nMAssay Description:Compound was tested in vitro for its ability to inhibit human leukocyte elastase (HLE)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285102(2,2-Dimethyl-propionic acid (2S,5R,6S)-6-chloro-3,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285108((2S,5R,6S)-6-Fluorosulfonyloxy-3,3-dimethyl-4,4,7-...)
Affinity DataIC50:  1.67E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285102(2,2-Dimethyl-propionic acid (2S,5R,6S)-6-chloro-3,...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281044((2S,5R,6S)-3,3-Dimethyl-4,4,7-trioxo-6-(toluene-4-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073221(CHEMBL3408420)
Affinity DataIC50:  3.35E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073228(CHEMBL3408421)
Affinity DataIC50:  5.57E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073222(CHEMBL3125572)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285103(Acetic acid (2S,5R,6S)-6-chloro-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073230(CHEMBL3125570)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50285103(Acetic acid (2S,5R,6S)-6-chloro-3,3-dimethyl-4,4,7...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073231(CHEMBL3125571)
Affinity DataIC50:  7.20E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073229(CHEMBL3408419)
Affinity DataIC50:  8.09E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073233(CHEMBL3408416)
Affinity DataIC50:  8.39E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073232(CHEMBL3408410)
Affinity DataIC50:  9.59E+4nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073227(CHEMBL3408430)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073226(CHEMBL3408439)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
University Of Montpellier

Curated by ChEMBL
LigandPNGBDBM50073224(CHEMBL3408441)
Affinity DataIC50:  1.49E+5nMAssay Description:Inhibition of human KLK7 using Suc-Leu-Leu-Val-Tyr-AMC as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281031((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.05E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285101((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285101((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  2.80E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285105((2S,5R,6R)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  9.50E+5nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285105((2S,5R,6R)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  9.50E+5nMAssay Description:Inhibition of porcine Pancreatic elastase without preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285104((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.16E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285110((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.20E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285104((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.21E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285110((2S,5R,6S)-6-Chloro-3,3-dimethyl-4,4,7-trioxo-4lam...)
Affinity DataIC50:  1.30E+6nMAssay Description:Inhibition of porcine Pancreatic elastase with 10 min preincubationMore data for this Ligand-Target Pair
In DepthDetails Article