Found 427 with Last Name = 'boström' and Initial = 'j' 
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.80nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 16.6nMAssay Description:Agonist activity at human CB1 receptor assessed as stimulation of [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 57nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 62nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 64nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 68nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMpH: 7.4 T: 2°CAssay Description:A GTP-gamma-S CB1 functional assay was used to assess the potency of the pyrazine derivatives. [35S]GTP-gamma-S binding assays were performed at 30 d...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of human Kv1.5 channel expressed in CHO cells by high throughput planar patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 82nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 88nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity at P2Y12 receptor (unknown origin) assessed as inhibition of GTPgammaS binding after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 94nMAssay Description:Antagonist activity at P2Y12 receptor in human washed platelets assessed as inhibition of fibrinogen-induced aggregationMore data for this Ligand-Target Pair
Affinity DataIC50: 95nMAssay Description:Displacement of [125I]-AZ11931285 from P2Y12 receptor (unknown origin) after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
