Affinity DataKi: 8.5nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataKi: 415nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataKi: 523nMAssay Description:Inhibition of human recombinant pro-MMP7 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human HDAC1 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human HDAC2 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 9.80nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins followed by sub...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant pro-MMP9 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC4 expressed in human 293T cells preincubated for 15 mins in presence of [3H]acetyl-labeled histones measured after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant MMP3 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant HDAC3/NCOR1 co-expressed in insect cells by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 69nMAssay Description:Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells preincubated for 3 hrs follo...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 69nMAssay Description:Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 co-expressed in baculovirus infected Sf9 insect cells p...More data for this Ligand-Target Pair
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 91nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant pro-MMP2 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant MMP14 catalytic domain by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant pro-MMP7 by spectrofluorimeterMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant pro-MMP1 by spectrofluorimeterMore data for this Ligand-Target Pair