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Found 60 with Last Name = 'bowman' and Initial = 'mj'
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59224(Pepstatin analog, 12)
Affinity DataKi:  96nM IC50:  360nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59223(Pepstatin analog, 11)
Affinity DataKi:  175nM IC50:  730nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59213(Pepstatin analog, 1)
Affinity DataKi:  220nM IC50:  350nMpH: 5.52Assay Description:The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59220(Pepstatin analog, 8)
Affinity DataKi:  600nM IC50:  2.90E+3nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59222(Pepstatin analog, 10)
Affinity DataKi:  650nM IC50:  2.50E+3nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59219(Pepstatin analog, 7)
Affinity DataKi:  720nM IC50:  2.70E+3nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59216(Pepstatin analog, 4)
Affinity DataKi:  1.13E+3nM IC50:  4.40E+3nMpH: 5.52Assay Description:The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479598(CHEMBL478672)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59217(Pepstatin analog, 5)
Affinity DataKi:  1.29E+3nM IC50:  4.90E+3nMpH: 5.52Assay Description:The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479600(CHEMBL504512)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479594(CHEMBL510483)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59214(Pepstatin analog, 2)
Affinity DataKi:  3.00E+3nM IC50:  5.90E+3nMpH: 5.52Assay Description:The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50370412(CHEMBL449777)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479603(CHEMBL446001)
Affinity DataKi:  6.80E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479593(CHEMBL498854)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479592(CHEMBL450301)
Affinity DataKi:  1.69E+4nMAssay Description:Inhibition of HIV1 protease by competitive inhibition assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479599(CHEMBL508493)
Affinity DataKi:  4.01E+4nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479596(CHEMBL454643)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479601(CHEMBL507784)
Affinity DataKi:  5.10E+5nMAssay Description:Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50410179(CHEMBL2096800)
Affinity DataIC50:  0.140nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410179(CHEMBL2096800)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Gamma-secretase from APP-transfected CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410182(CHEMBL2096799)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410183(CHEMBL2096801)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150691(311951 | CHEMBL437635)
Affinity DataIC50:  16nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150696(CHEMBL436787 | methyl 2-[(2R,3R)-2-[(2R)-2-{2-[(2R...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150689(311952 | CHEMBL411599)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410178(CHEMBL2096802)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150693(CHEMBL415576 | methyl 2-[(2R)-2-[(2R,3S)-3-(benzyl...)
Affinity DataIC50:  90nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150690(CHEMBL409305 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150688(311440 | CHEMBL413823)
Affinity DataIC50:  780nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150694(311383 | CHEMBL437440)
Affinity DataIC50:  910nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479601(CHEMBL507784)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479597(CHEMBL466288)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479604(CHEMBL449860)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479598(CHEMBL478672)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50150687(CHEMBL410969 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479600(CHEMBL504512)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59221(Pepstatin analog, 9)
Affinity DataIC50:  4.30E+3nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366941(CHEMBL1790139)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50410181(CHEMBL2096796)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366939(CHEMBL1790126)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59215(Pepstatin analog, 3)
Affinity DataIC50:  5.80E+3nMpH: 5.52Assay Description:The competitive assay requires two inhibitors to act by a purely competitive mechanism, whereas the binding site of on the inhibitors has been establ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid scaffolding protein(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Purdue University

LigandPNGBDBM59218(Pepstatin analog, 6)
Affinity DataIC50:  5.80E+3nMpH: 5.52Assay Description:A zhang-poorman assay confirms a competitive inhibition mechanism or inhibit HIV-1 PR as a dimerization or mixed type inhibitor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366938(CHEMBL1790133)
Affinity DataIC50:  5.90E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479605(CHEMBL500554)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366936(CHEMBL1790128)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366940(CHEMBL1790135)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50479595(CHEMBL507080)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of HIV1 protease by continuous fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50366937(CHEMBL1790127)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibitory concentration against ProteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50150695(CHEMBL414031 | methyl 2-[(2S,3S)-2-[(2S)-2-{2-[(2S...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory activity against Gamma-secretase in HeLa cells expressing APP-reporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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