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Found 40 with Last Name = 'boyne' and Initial = 'm'
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16300(INH-NAD Adduct | ISONICOTINIC-ACETYL-NICOTINAMIDE-...)
Affinity DataKi:  0.75nM ΔG°:  -51.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373348(CHEMBL264434 | PT13)
Affinity DataKi:  1nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373347(CHEMBL264175 | PT15)
Affinity DataKi:  1nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16298(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Affinity DataKi:  1.10nM ΔG°:  -50.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataKi:  9.40nM ΔG°:  -45.4kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Affinity DataKi:  11.8nM ΔG°:  -44.8kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16299(14PP | 2-phenoxy-5-tetradecylphenol)
Affinity DataKi:  30.3nM ΔG°:  -42.5kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  200nMAssay Description:Inhibition of Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataKi:  220nM ΔG°:  -37.6kJ/molepH: 6.8 T: 2°CAssay Description:Inhibition constants (Ki) were calculated by determining the kcat and Km (DDCoA) values at several fixed inhibitor concentrations. The inhibition dat...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16298(5-Octyl-2-phenoxy-phenol | 5-heptyl-2-phenoxylphen...)
Affinity DataIC50:  5nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataIC50:  11nMAssay Description:Inhibition of 1 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16297(5-Hexyl-2-phenoxy-phenol | 5-hexyl-2-phenoxylpheno...)
Affinity DataIC50:  11nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16296(5-Pentyl-2-phenoxy-phenol | 5-pentyl-2-phenoxylphe...)
Affinity DataIC50:  17nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373350(CHEMBL264416)
Affinity DataIC50:  48nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373347(CHEMBL264175 | PT15)
Affinity DataIC50:  55nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373348(CHEMBL264434 | PT13)
Affinity DataIC50:  62nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16295(4PP | 5-Butyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Affinity DataIC50:  80nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373349(CHEMBL264417 | PT12)
Affinity DataIC50:  90nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373340(CHEMBL260399)
Affinity DataIC50:  130nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16299(14PP | 2-phenoxy-5-tetradecylphenol)
Affinity DataIC50:  150nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373336(CHEMBL259138)
Affinity DataIC50:  160nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373355(CHEMBL264415 | PT10)
Affinity DataIC50:  180nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373337(CHEMBL405655)
Affinity DataIC50:  236nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373339(CHEMBL261355)
Affinity DataIC50:  306nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373343(CHEMBL263646)
Affinity DataIC50:  580nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373334(CHEMBL258932)
Affinity DataIC50:  650nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)
Affinity DataIC50:  1.00E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373354(CHEMBL404984)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373341(CHEMBL405653)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373345(CHEMBL262360)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373351(CHEMBL408149)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373346(CHEMBL264176)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373352(CHEMBL262343)
Affinity DataIC50:  1.93E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM16294(2PP | 5-Ethyl-2-phenoxy-phenol | 5-butyl-2-phenoxy...)
Affinity DataIC50:  2.00E+3nMpH: 6.8 T: 2°CAssay Description:The assay measured the NADH-dependent catalysis of a DD-CoA substrate as a decrease in 340 nm absorbance resulting from conversion of NADH to NAD. Th...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373344(CHEMBL407324)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373342(CHEMBL428967)
Affinity DataIC50:  3.22E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373353(CHEMBL404983)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373335(CHEMBL258931)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373333(CHEMBL264679)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Suny Stony Brook

LigandPNGBDBM50373338(CHEMBL429332)
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of 100 nM Mycobacterium tuberculosis H37RV InhAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed